Protein Info for mRNA_120 in Rhodosporidium toruloides IFO0880

Name: 8488
Annotation: K10413 DYNC1H dynein heavy chain 1, cytosolic

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 500 1000 1500 2000 2500 3000 3500 4000 4364 PF08385: DHC_N1" amino acids 274 to 857 (584 residues), 420.3 bits, see alignment E=8.9e-129 PF08393: DHC_N2" amino acids 1370 to 1771 (402 residues), 392.2 bits, see alignment E=2e-120 PF12774: AAA_6" amino acids 1915 to 2257 (343 residues), 440.2 bits, see alignment E=2.8e-135 PF07728: AAA_5" amino acids 2246 to 2379 (134 residues), 39.4 bits, see alignment (E = 4e-13) PF17852: Dynein_AAA_lid" amino acids 2448 to 2575 (128 residues), 63.1 bits, see alignment (E = 2e-20) PF12775: AAA_7" amino acids 2590 to 2762 (173 residues), 121.5 bits, see alignment (E = 2e-38) PF12780: AAA_8" amino acids 2934 to 3206 (273 residues), 188.1 bits, see alignment 1.3e-58 PF12777: MT" amino acids 3221 to 3550 (330 residues), 144.8 bits, see alignment 2.3e-45 PF12781: AAA_9" amino acids 3582 to 3801 (220 residues), 235.9 bits, see alignment 2e-73 PF03028: Dynein_heavy" amino acids 4054 to 4169 (116 residues), 92.6 bits, see alignment (E = 1.3e-29) PF18198: AAA_lid_11" amino acids 4171 to 4343 (173 residues), 112.3 bits, see alignment (E = 1.4e-35)

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (4364 amino acids)

>mRNA_120 K10413 DYNC1H dynein heavy chain 1, cytosolic (Rhodosporidium toruloides IFO0880)
MQDRRPSSPAVDGAESPPTATPGPRNQFDLAAFRKYLGQLLPLLIEAESADLESLFERSD
FSERATRWANDPNAGALYVVKQREERDADEQQDDSLLDTFTYSLTSSLSYSPLQSATLAL
IKHVPILDSSLPLASQLHFLNLFGPASSSSSSNALVAGATAGSVVYEGLHRLVHYGVAPA
FEAYVESKARKDAAGRAVEDSKDADVKMGIPMTKKKFAELELSLLHLQQNVEIPDIVLSI
HPVVSAAVSQAEASGIRPFVDLIDSALFSDSAFLNKLQSEVNNWVKEVQKVTKLSRDVAS
GTASQEVNFWLSMEKALEGIEKQLKSEPVQLSLDILKHAKRFHATVSFIADTGLNDAFKT
VHDYNVLMKDFPLNELLAATDLNKIKDSINQIFLHVNKKLKLSPYPVRRILPLVEAISRD
LENQLHKVLSSQRLTYLDYPLFEQAMRAAEGVFQAWDESFKEFTNVAREVTRKRGERFIP
IKIDPGHAKLQERVLYFRHFRKQHHQLQVMVGPLSSETKRSTAVNGDGAKENGDVDGELA
REWSSTLGDIDMEVEVRQAYEGIKGIDVLDVSDDGTQIWIAAETGYNERVARVENHIISR
LRDRLGGAKNANEMFRVFSKFNALFVRPKIRGAIAEYQSQLIDSVKDDIRRLQDKFKSGY
QSSEAYQMSQLRDHPPISGAIIWARQIERQLSGYMKRVEDVLGTEWSHYADGQRLQTESQ
SFRAKLSTRPIYDAWLVDINRRNLQISGRLFNITKSRQQAGALQLTVNFDPQIITLFKEV
RNLLWLGFQVPHTISNVAKDAKRVYPYAVSLMETVRTYSQTVAKLEANPDIASLVATSHK
KAQEQIAKGMSYRWDHFVNTFDNRSLPYAGASESSGSKHTHWVREFASIVSEFQDRTDHL
IALWADVSRTVDELGTCAYTREAFSTLLASLQKTIDTLNLEGYANLESWTLALDKRVEAK
LVGRIRAVIERWCGEFSKTPEALAAESNRYGASGKKAAAARDNQPEDGLPLETILHEVRI
QNQVIYLDPPMEQARATWYRQLQTWLGVVCGLTRIQSSRYEIGLSIRAAQPGALDYSTLL
ASLTDGTLERPFALVEAKLEEVGGYVDKWLQFQSLWDLEAEYVYSQLGDRLSAWQQLLLE
IRKTRSTFDNSETQRSFGVAVIDYEQVQSKVNAKYDAWQRNLLSRFGGKLGVAMKETHAA
VAKARHDLEQHSIETSSTAATVTFITFVQDVKRKLKQWAPEIEIFSSGQKTLERQRYQFP
SDWLYLDQVENEWSAFNEILKRKDASIQEQLAGLQLKVVAEDKVLQGRIEETVADWDANK
PIQGSLKAEAAMNAIGVFEGRVNRLKEQHDMLSRAKESLDLEATKDDRLEPVLEEIRDLK
AVWTALSGVWAQVGDLRDTAWQSVQPRKVRQQLDSLLASTREMPSKMRQYAAFEFVQESL
RGYLKSNSLVANLKSEALRERHWRQLYKSLRVAGHYSPSTMTLGTVWDLDLKRNETAIRD
VIVQAQGEMALEEFLKQVKETWTGYALDLVNYQNKTRLIRGWDDLFAKCGENVNSLNAMK
LSPYYRVFEEEASAWEDRLNRIHLLFDVWIDVQRQWVYLEGIFSGSTDIKHLLPVESQRF
SNINAEFLAVMKKVFKSPLVLDVLNIPGAQKSLERLADLLSKIQKALGEYLERERSSFPR
FYFVGDEDLLEIIGNSKDILRVSKFLKKMFAGLSSLKLDDELSRIDGMVSREGEEVPFST
PIVLSEYPRINDWLARLESEMKTSLAQLLARSHADLVAFYADPAGLDAGRFLRWIEATPA
QLVVLAIQIAWTDGVESALQAGGALDRPLAVILRSLEVLADAVLGDLQPIQRRKCEHLIT
ELVHERDVVRRLAQDGVQSAADFAWLYHMRFYLDVGKENVLEQLQVKMASASFFYGYEYL
GVPDRLVQTPLTDRCYLTLTQALDARLGGSPFGPAGTGKTESVKALGVALGRFVLVFCCD
ETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERILSAVSQQIQSIQLGLGETVTNPSHEI
ELVGRQLRINPDTGIFITMNPGYAGRSNLPDNLKKLFRSIAMTRPDRELIAQVMLFSQGF
RTAEKLASKVVPFFNLCAEQLSSQPHYDFGLRALKAVLVSAGHLKRARLQAVTNANGSES
VDISEQEIVIQSVTETIVPKLVAEDVPLLTSLLADVFPGIDYIPVDLEDLKKHILDICKE
RNLVAGDVWLQKVVQLYQIQNIQHGLMMVGPSATGKTSAWRVLLAALERLTGIEGVSYVI
DPKAIAKDALYGTLDPTTREWNDGLFTHVLRKIVDDVRAESSKRHWIVFDGDVDPEWVEN
LNSVLDDNKLLTLPNGERLNLPPNVRIMFEVESLKYATLATVSRCGMVWFSDDAVSPDML
CRNYLDATRSTPLDVADEDASFARQPQSDGDEVSAVLATQQLVTAKLEPFFERDGLVAKA
LDFAAGVDHIMDFTPSRALTTLFSLLNKSIRTIAEYNAQHPDFPLQGDSVEAYILKRLLL
GLVWAFTGDSKLDTRAKMGDFLRNQSGLDFPPLGPGGSLIDFDVQVSTGDWVSWQNSVPT
IEVETQAVTSPDVVIPTMDTARHEEVLYSWLSEHRPLLLCGPPGSGKTMTLFSALRKLPD
LEVVGLNFSSATTPDLILKTFEQHCEYRKTPNGVVLAPTQIGRWLVLFCDEINLPATDQY
GTQKVISFLRQLVEQNGFWRTTDKAWVRLENIQIVGACNPPTDPGRVPLTHRFLRHAPLV
MVDYPGETSLKQIYGTFTRALLKVVPPLRGFAEPLTDAMVDFYLASQARFTTDAQAHYVY
SPRELTRWTRGIYEAIKPLDALSVEGLVRVWAHEALRLFQDRLVTEEERKWTDDKIDEIA
LAHFPTIDRDEALARPILYSNWLSKHYVPVDREELREYAKARLRVFYEEQLDVPLVLFND
VLDHVLRIDRVFRQVQGHLLLIGTTLSRFVAWMNGLSVFQIKVHNKYTGDDFDDDLRAVL
RRAGCKGEKIAFIMDESNVLDSGFLERMNTLLANAEIPGLFEGDEHASLMTACKEGAQRD
GLMLDSHDELYRWFTSQVARNLHVVFTMNPPSGGLASRAATSPALFNRCVLDWFGDWSDQ
AFYQVGFEFTNTLDLDAAGYTAPANFPTAYRQLSVPPVHRTAVVNALVHVHQSMYESNAR
LARRQGRVNHATPRHYLDFVNQYVRLFNEKRDELEEQQRHLNVGLDKLHETVVQVEDLRK
SLAVKRTQLEAKNAEANDKLKRMVVDQQDAEQKKVASIEMSTALEKQKHAIAERREIVMG
ELADAEPAVEDAQAAVSNIKKQQLTEVRSMANPPEAVKMSMEAVCILLGHRIEGWKSVQA
VLRSESFIASIVNFDTAHMMTRQLRDKMRNDYLSRPSFNFETVNRASKACGPLVKWVIAQ
VNYSSILDKVGPLREEVQMLEDQAETTMHQASALSSMISELEARIAAYKDEYAALISETQ
AIKSEMERVQTRVDRSVKLLDSLSSEKSRWEAGSKTFEEQMSTVAGDVLLSAAFLAYAGY
FDQSNRQAMWQGWANHLSDAGIKYKPELSLTEYLSTADERLEWHGRGLPTDELCVENAIM
LKRFDRYPLVIDPAGQATSFLLNEFRDRKITVTSFLDEAFLKNLESALRFGTPILIQDVE
HLDPILNAVLNKELRRAGGRVLIRLGNQDIDFSPSFTMFLATRDPSVEFAADLNSRVTMV
NFSITRASLQTQSLAQVLKVERPEIDRKRSDLLRLQGEFRARLHQLERSLLAALNGSQGN
ILDDDKVIETLETLKKEAADIMRKVEETDTVMAEVDEVTNEYLPLAQACSSVFFILDDLH
LLNRFYQFSLRFFLDIFDYVLLNNPSLKGIADAHERTRILFDDLFTHVFRRTSRALLHSD
HLTLAVLLAQIKLRGQGEELDEQELSFLLEGGETTAATSTTASIAILDPTQQQRLQAFER
LGVFRDVRSNLVEREGDWQTFLASAAPETVVPQVWPELDPVHAALRNALIVKCLRPDRLI
PALTAFVAVVFKRDLFAETTYDLSDMVQNEVAAASPVCLCSVPGYDASYRVDNLVAATSA
RCTSVAMGSQEGFALADQAIAASARTGNWVLLKNVHLAPTWLSQLEKRLQSLNPNRAFRL
FLTMEMNPAIPVNILRQGRVLMNEPPPGIRANILDSLRTLNPARLAHGPAEKTRLYFLVA
WFHAVVQERLRYVPLGWSKVFEFNDSDQDAALNTIDAWLSSAAKGRANIDPAAIPWQAIR
SLVRETVYGGKIDTEFDQSLLDSFVETLFSPRAYEVDFDLVSSGENEAGLKVPDAVHLDQ
FLEWASQLPEQEPPSYLALPPTAERVIAAAQGTFGFKSLSQPFS