Protein Info for mRNA_210 in Rhodosporidium toruloides IFO0880

Name: 8578
Annotation: K08675 PRSS15, PIM1 Lon-like ATP-dependent protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1226 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF02190: LON_substr_bdg" amino acids 184 to 534 (351 residues), 104.5 bits, see alignment E=2.2e-33 TIGR00763: endopeptidase La" amino acids 186 to 1200 (1015 residues), 1021.9 bits, see alignment E=0 PF08298: AAA_PrkA" amino acids 652 to 710 (59 residues), 21.5 bits, see alignment 3.2e-08 PF07728: AAA_5" amino acids 686 to 819 (134 residues), 23.3 bits, see alignment E=1.7e-08 PF00004: AAA" amino acids 686 to 822 (137 residues), 78.6 bits, see alignment E=1.9e-25 PF07724: AAA_2" amino acids 687 to 808 (122 residues), 22.8 bits, see alignment E=2.8e-08 PF05362: Lon_C" amino acids 993 to 1200 (208 residues), 217.6 bits, see alignment E=4e-68

Best Hits

Predicted SEED Role

"ATP-dependent protease La (EC 3.4.21.53) Type I" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent (EC 3.4.21.53)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.53

Use Curated BLAST to search for 3.4.21.53

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1226 amino acids)

>mRNA_210 K08675 PRSS15, PIM1 Lon-like ATP-dependent protease (Rhodosporidium toruloides IFO0880)
MLPASMRARTSLASSRASRTAFARPPSSSLRTTSTTPRLNARSPLASTSRLTLDVPASSR
ALSTSARLDLASPLRPSPPLSFPRAPRLSLREQQNGENDEFDGDEGREGGEGEGEEKVPV
RRPGVPQTEQPRSGLRNPSSAGTSAGTRGSGGAAEGGAAGGRSGDGEGNSSVAKSSVPNV
YPQVMALPITRRPLFPGFYKAVVVRDPEVIKAIKESISRGQPYLGAFLLKDENADSDVIT
DPNSVHPVGVFCQITSTFPTNPTRPPNPNSDEKPEEPGLTVVLFPHRRIRIDELLPVGTP
NKSRKSTETEMHHPEPHSVVDEHRPHIDGPQRPEEPAFVGDAPLTPESASESKQEPELEQ
SPAPIDRDASTEAKRPDEPEFVEGKERADVVVDDEGRVVREGEGQGQGEGEAKEAAESSD
HQSFQTAYLHNYGVSIANVSNLEMEPYDAKSQVVRAISGEIVSVFKEIASLNPLFRDQIA
NFSMSLTAGNIFEEPEKLADFAAAVSAGEVNELQDVLESMVLEDRLQKGLLVIKKELMNA
QLQNKISKDVESKIAKRQREYILQEQLKGIKKELGLESDGKDKLVEKFKEKAKSLLMPEA
VQKVFDEELNKLGTLEPAASEFNVTRNYLDWLTSIPWGHHTKENFDLTHAVKVLDEDHYG
LKDVKDRILEFLAVGKLRGTVEGKILCFVGPPGVGKTSIGKSIARALDRQFFRFSVGGLS
DVAEIKGHRRTYVGAMPGKIIQALKKVQTENPLVLIDEVDKIGRGHNGDPSSALLEMLDP
EQNAQFLDHYLDVPVDLSRVLFVCTANTLDTIPAPLLDRMEVLEVSGYITEEKAAIASKY
LAPAAKEGAGLKNADVELQDDAVAALIRYYCRESGVRRLKQQIEKVFRKAALKIVQDIGE
PALPESAAKTIQPEAAVTKEAESKKEETTSTDSTPSAPADKAVEKQDGDSTPASTASPSS
AATPDSSVTAEERKTTTSVRQPLEVPSDVHVRISAENLLDYVGPPLYQKDRLYTKISPVG
VSTGLGYLGNGSGAVMPIEVTSMPGQGIQLTGKLGEVIKESAQIALAFLRAHAYDLGLTS
DPDKDLLEKRAIHLHMPEGAIGKEGPSAGIAILTAFVSLFSKRGVSSELAMTGEVTLAGQ
VLPVGGLKEKTLAAHRAGIRKLILPLGCKADIEHNVPESVKEGIEIVYAENVAEVLREAF
AGSPIADKINSGALNDILIPREEAKR