Protein Info for mRNA_263 in Rhodosporidium toruloides IFO0880

Name: 8631
Annotation: K01537 E3.6.3.8 Ca2+-transporting ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1369 transmembrane" amino acids 260 to 289 (30 residues), see Phobius details amino acids 317 to 337 (21 residues), see Phobius details amino acids 484 to 506 (23 residues), see Phobius details amino acids 525 to 552 (28 residues), see Phobius details amino acids 1007 to 1028 (22 residues), see Phobius details amino acids 1034 to 1056 (23 residues), see Phobius details amino acids 1077 to 1102 (26 residues), see Phobius details amino acids 1124 to 1141 (18 residues), see Phobius details amino acids 1161 to 1184 (24 residues), see Phobius details amino acids 1194 to 1214 (21 residues), see Phobius details amino acids 1298 to 1315 (18 residues), see Phobius details PF00690: Cation_ATPase_N" amino acids 211 to 283 (73 residues), 40.9 bits, see alignment 3.3e-14 PF00122: E1-E2_ATPase" amino acids 354 to 559 (206 residues), 134.8 bits, see alignment E=6.2e-43 PF00702: Hydrolase" amino acids 578 to 960 (383 residues), 56.2 bits, see alignment E=1.6e-18 PF13246: Cation_ATPase" amino acids 672 to 761 (90 residues), 65.1 bits, see alignment 1.3e-21 TIGR01494: HAD ATPase, P-type, family IC" amino acids 915 to 1027 (113 residues), 104.4 bits, see alignment E=5.3e-34 PF00689: Cation_ATPase_C" amino acids 1033 to 1213 (181 residues), 156.1 bits, see alignment E=2.1e-49

Best Hits

Predicted SEED Role

"Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)" (EC 3.6.3.3, EC 3.6.3.4, EC 3.6.3.5)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.3, 3.6.3.4, 3.6.3.5

Use Curated BLAST to search for 3.6.3.3 or 3.6.3.4 or 3.6.3.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1369 amino acids)

>mRNA_263 K01537 E3.6.3.8 Ca2+-transporting ATPase (Rhodosporidium toruloides IFO0880)
MDPPPAPSTPPLAPPIPTVQVSPAPDPTPSATEDSPPSSTERRLSLAPTVASSAGASGTD
AAPPSPTPSSEPLFNARTTTSLRDNLDAPSFASTVPDSNDGHAPTPHVSNACAPKDLEAG
LDAAGKPLTATGDGLRDASSPGVEDTALPADEEKKSKILGIFPRRAKKPQEVYKIHDPPP
EEMAPFDTSLTPSALYNLVDPKSFEHMRELGGVKGILGGLKTDAKVGLQEAGGEGAVAEG
EDRRRVYGENRVPGRKPKSFLALCWAAYTDKVLIILSVAAIVSLALGLYQDLGTPPDTYF
STSCPPTNMCTEPQVDWVEGVAITVAILIVVLVGSVNDYQKERQFQKLNAQKEERSVKVL
RGGQERLMSVYDVVVGDILFLEPGEIVPVDGIFLGGHNVRCDESGATGESDAVRKAPYDE
IEAEGGKGKTDCFMISGSKVLEGVGKYVVTSVGMNSFHGKIMMSLQGDTEDTPLQLKLNA
LAELIAKLGSAAGLLLFTALMIRFFVQLKTMPDRSANDKAQAFIQVLIIAVTVVVVAVPE
GLPLAVTLALAFATRRMTKMNLLVRVLGACETMANATCVCTDKTGTLTTNKMTVVAGSIG
VHLKFADRLAENSKRTNANDDRDPEKVVEDEKAAEEAADPQPRKGRLDFSADMTAISSHA
SPALRKLLNDSIVINSTAFEGTDEHGATGGFVGSKTETALMSFAQAQGWPHYRAVREGAH
IVQMVPFSSERKCMGVVVQLPNGKHRLYLKGASEVLAKLSTRHVTVQENGGEAGSEDDDV
PTAEFDDETRGNISRTIIFYACQSLRTIALCSRDFASWPPKGAQTNAEGEVAYEDMANDL
TLIAITAIEDPLREGVAKAVATCQRAGVMVKMCTGDNVLTARSIATQCGIFTKGGIIMEG
PVFRKLSDSQRLSVVPNLQVLARSSPEDKKILVETLKSMGEVVGVTGDGTNDGPALKTAN
VGFSMGIAGTEVAKEASDIILMDDNFASIVSAIMWGRCVNDSVRKFLQFQLSVNITAVVI
TFVTAVASEEESSVLTAVQLLWVNLIMDTFAALALATDPADPESLERKPDRKTAPLISVQ
MWIMIIGQAIYQIVVALVLNFAGHQILSLDSSDPGQRIDQDNELMTLIFNAFVFSQIFNM
LNARRLDRKLNIFVGIHRNIWFMLIFVIMVGGQALIVNVGGAAFQVVRIGGRDWAISIII
GLISLPIAVLLRMIPPEPVERFMVRAHLYPDLSKTDLPSVNKAAEEYKWAEGIQRAIDGL
KVYSTVRGGRARATNILKFRRPRSRAQQLRAMDMQPTHLLAMVPTLVIGSVGAGWRPESG
SLDDPAAHDPSLSTQQLVEKGLGQLQPMSPRGAHSRSPSMSTTLPPVKE