Protein Info for mRNA_267 in Rhodosporidium toruloides IFO0880

Name: 8635
Annotation: K03381 catA catechol 1,2-dioxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 PF04444: Dioxygenase_N" amino acids 25 to 97 (73 residues), 87.2 bits, see alignment E=5.5e-29 PF00775: Dioxygenase_C" amino acids 106 to 292 (187 residues), 155.7 bits, see alignment E=9.4e-50

Best Hits

KEGG orthology group: K03381, catechol 1,2-dioxygenase [EC: 1.13.11.1] (inferred from 52% identity to bfu:BC1G_06739)

Predicted SEED Role

"Catechol 1,2-dioxygenase 1 (EC 1.13.11.1)" in subsystem Catechol branch of beta-ketoadipate pathway (EC 1.13.11.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.13.11.1

Use Curated BLAST to search for 1.13.11.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (304 amino acids)

>mRNA_267 K03381 catA catechol 1,2-dioxygenase (Rhodosporidium toruloides IFO0880)
MPSAAPDYSAYTQSVIDAIGSKASPRVKQAFPILIKHLHAAIVEAEVTVDEWLEACDLLI
EAGKVSSEKRNEMVLVSDVLGVESLVDMMEHARYAQAGRDATFSAILGPFYRQGVPPQPN
GSSIIRMKEPGAPFVHLHGTVTGKDGKPLKGAFVDVWHDAPDGFYDSQSPDKPEHHCRGR
FETDSNGNYSLVALKPTPYPIPFDFSAGKLLNMMDRHPYRPAHIHFHVQAPGHKTLVTQV
FSRDSQYLDDDAVFAVKDSLIVDFVKPTAPLPKGGEFDEEIKYELKYDITLAGDGEVDNS
QYQG