Protein Info for mRNA_325 in Rhodosporidium toruloides IFO0880

Name: 8693
Annotation: KOG0054 Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1441 transmembrane" amino acids 262 to 281 (20 residues), see Phobius details amino acids 291 to 306 (16 residues), see Phobius details amino acids 342 to 385 (44 residues), see Phobius details amino acids 448 to 471 (24 residues), see Phobius details amino acids 855 to 872 (18 residues), see Phobius details amino acids 906 to 931 (26 residues), see Phobius details amino acids 983 to 1002 (20 residues), see Phobius details amino acids 1007 to 1025 (19 residues), see Phobius details amino acids 1039 to 1058 (20 residues), see Phobius details amino acids 1089 to 1109 (21 residues), see Phobius details amino acids 1121 to 1139 (19 residues), see Phobius details PF00664: ABC_membrane" amino acids 222 to 497 (276 residues), 99.2 bits, see alignment E=5.1e-32 amino acids 902 to 1108 (207 residues), 109.1 bits, see alignment E=5e-35 PF00005: ABC_tran" amino acids 591 to 724 (134 residues), 65.5 bits, see alignment E=1.2e-21 amino acids 1202 to 1356 (155 residues), 98 bits, see alignment E=1e-31

Best Hits

Predicted SEED Role

"ATP-energized glutathione S-conjugate pump, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1441 amino acids)

>mRNA_325 KOG0054 Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily (Rhodosporidium toruloides IFO0880)
MAEASSAAIESHVLGADGGPKAPLTSEDAVKQGSGAPGGTVGGSDESVTTAADEQDVRKD
DGKGEDVEKDEEKEVKVRHRWSIFDPFNFKPPPPPPASMDDAETIRISQANWLSEFTFWW
LQPLLVLGYKRELEATDLPKMDETREAGLLADKFEANFARRRKDVEDWNRGLDNGSYVPS
SLQKMRWRAFAAMGFARADGRREVGMAMALSDTFFWSFWSAGIYKVIGDVAQTTSPLVMR
QIIKLVQQSYAAKQAGEPLPGIGRGIGLAIGLFLMQLFMSVCQNNTFSRSGQVGVLARAA
LIASLYRKAFRMSGKARVEHTNAKLTSHISTSMSRIEWSSTFFHFSYTCIIQLVEIVVIL
LCTIGVTSLAGVGIVLLAIPMQTYAMRKLFQGRRKVQKHTDDRIKSISELLSGIRVVKFF
AWEGPIVSKVGESRRRELGGIRKLLTIRAATQAMAMSLPVLSSVLVFAVYSLTGHSQQNP
AEIWTALSLLNLLRQPLMIPNSLSTMTDAYSAMKSLVPCFMADELPEELFVRDDKADLAL
QVKDATFVWESSAPPSSEKAGKGKSGKKAKKEQGAADEKGVAAADEPSKVEDINLEVPRG
QLLCVVGSVGSGKSSLLQGCIGEMRRTSGDVVFGGSIAYCAQSAWIMNTTLRANILFGRP
FDEQRYWDCVRAACLLADLDQLPAGDQTEIGEKGITLSGGQRQRVAIARTLYYDADIVLL
DDPLSAVDAHVGAHIFERAIQGMLKEKTRILVTHAVHLLPKADAIIVMENGRIAERGSFD
ELMAAGGPFSRFAQEYGVAAAAEASNDVKPTATGGAAQVAPKGKASNRPLMQKEEQASGS
VGWSTWKSYFRAADGYYTVPLVLGSLVLMSAGQRIPSLTPSHPVLSQFALTWWQEGKFGL
GQNQFIGLYAGLGISSAIFTFVLGAATIWFGTTAARNLHHMALEKVTQAPMSFFDTTPLG
RLMNRFSKDTDSIDNRLNDSLRMCLATVAQIGASIIVIAIVYPYFLIPTAFVLALFVMTS
NFYRASARTIKRHDNVLRSFLYAWFGESLTGLSTIRAFGEKERFLRGNERYIDLENRAWF
LTVCNQRWLAIRVDAWGALLVLIVALVAVGERTTIPSSKTGLILAVTLAMQASIAMLIRQ
TAEVENNMSSIERFEWYAKSLPQEAPAIINDTAPPSTWPNQGAVTFRDVEIRYRPELPSV
VRNFNVQIRGGEKVGVVGRTGAGKSTLTQALFRILETYKGTIEIDGLDISKLGLTQLRER
LAIIPQEPLLFSGTLRSNLDPFGLYDDARLYDALRRSWLVDRTAGADGSGQVSRFTLDTR
VEDEGANMSLGERSLVSLARALVKDAKVIALDEATASVDLETDAKVQATIRSEFKDKTLL
IIAHRISTIVGCDKILVMDRGEIQSFANPLELFDRGDGIFHSLCVQSSISREDIVKAQAD
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