Protein Info for mRNA_390 in Rhodosporidium toruloides IFO0880

Name: 8758
Annotation: K00869 E2.7.1.36, MVK, mvaK1 mevalonate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 TIGR00549: mevalonate kinase" amino acids 78 to 328 (251 residues), 165.4 bits, see alignment E=9.7e-53 PF00288: GHMP_kinases_N" amino acids 110 to 191 (82 residues), 52.4 bits, see alignment E=5.2e-18 PF08544: GHMP_kinases_C" amino acids 273 to 341 (69 residues), 21 bits, see alignment E=3.5e-08

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (413 amino acids)

>mRNA_390 K00869 E2.7.1.36, MVK, mvaK1 mevalonate kinase (Rhodosporidium toruloides IFO0880)
TAIAGAIDLRCYCLAESRSDGQLSLVLPDLGYSQTWDIASLPWDKVDALSSTVLKSGPKS
DAVPDQELLTLLANKFVHQDKLKAVQAAQAFLYLYLHLAVSSGIKPAQTYTVRSGLPISA
GLGSSAAYSVAVASSLLYSHGILPAPASSPSADSTIPIEHANMVNSWAFLAEKVIHGTPS
GVDNTVATLGGAIAFRRAVKGREGSMDVLKGFDKVEFLLTDTKVPRDTKTLVAGVARRKL
EEPDTINPLLTSIQRISDEAQACLSSTTLSRSEQLDTLSRLVEQNHQHLVSLGVGHVALE
AVRSKTKEQPWGLATKLTGAGGGGCAVTVVPDSFPEDKLTALRAALANSGFETYATSVGG
RGFGVLIPTHGSQLETAEGGVELSAIPQQKRFEEAQTEELGRWAEEAGVWVCA