Protein Info for mRNA_465 in Rhodosporidium toruloides IFO0880

Name: 8833
Annotation: K10858 PMS2 DNA mismatch repair protein PMS2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1037 TIGR00585: DNA mismatch repair protein MutL" amino acids 1 to 332 (332 residues), 287.5 bits, see alignment E=8.9e-90 PF13589: HATPase_c_3" amino acids 23 to 112 (90 residues), 33.9 bits, see alignment E=5.3e-12 PF01119: DNA_mis_repair" amino acids 251 to 351 (101 residues), 74 bits, see alignment E=1.7e-24 PF08676: MutL_C" amino acids 835 to 995 (161 residues), 72.1 bits, see alignment E=8.8e-24

Best Hits

Predicted SEED Role

"DNA mismatch repair protein MutL" in subsystem DNA repair, bacterial MutL-MutS system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1037 amino acids)

>mRNA_465 K10858 PMS2 DNA mismatch repair protein PMS2 (Rhodosporidium toruloides IFO0880)
MAIQAIDKSSVHRLTSGQVVIDLQTAVKELVENALDAGATKIEVRFRDYGLEAFEVLDNG
KGIVKDDWPSIALKHHTSKLASFDELASVATLGFRGEALSSLCGVATFSMITSTSSNPPI
GTSLTFAHSGECIVGGKVARERGTTVKVERLFDTLPVRRKELVKNVKREFGKAIELINSY
AIINTGVRFDVRNTAKGKTQTHLQTPTSSSIRSNYASIFAAKDLASLTDFNLTLEVPTDK
SILKRIEGAMEATTTIKVKGLISKPAAPHGRTTSNRQFFYINGRPFSPTKIAKAVNEVYK
SYNSNQFPVVVADFQLAPDAYDINVSPDKRTIFLHSETNLILALKEQLAKFFEPQRGTFA
MQAIGPAKGKEKVQEPEEAGVLVKEEAEDSAFSEERPRKRRKDSHAPSSELDPPPRVTTP
VERAAPSTSSNIRRSISVTPVVDPFPTLSGEEAVLPTPPPDFAHPPSPAGADGDGADANL
PATPERQSPPLADSPPDSSTAALFLPPSPTPRPTSPSSSPSRRRTSPSPAPRPPPAPSRN
LKQPTLPFAPVRAAAGSSRGSRGTRNAGVGKEEPGARMKGMLQKFLRGSQAQAQGDADGE
PDSDGGQESDESEENDEREDDGANVEMAGGEEEGQDGAEIERDEIAADVDESARPRGYEV
ERVDDSGAADEAAEQHIEDVVLVVEDSFKAASPPATAVDDDLEIASASCICLHGSQDSDI
EIQEATSTSARPPSAAAPRVALHDSPLPFGAASAEVAGTVIAADADLDVDFDAIQASWTA
TVGDPLRQRSPARASANSEEDEDTLAGAGVDEQEDVAEATLSRVVSKQDFEAMEVVGQFN
LGFIIARRKVVAEPANGDGEPGVHDDLFIIDQHASDEKYNFERLQAETVIQSQRLLAPRS
LGLPSADEITALEHLDLLRLNGYEVAIDEDAQIGERVKLVAQPVSKETVFDVGDFEELIH
LIESRGGGEVVRPSKARRMFASRACRKSVMIGKALSASQMYSIIRHMGGMDQPWACPHGR
PTMRWVCRSACPSARLD