Protein Info for mRNA_487 in Rhodosporidium toruloides IFO0880

Name: 8855
Annotation: HMMPfam-Thioredoxin-PF00085,HMMPfam-PITH domain-PF06201,PRINTS-Thioredoxin family signature-PR00421,ProSitePatterns-Thioredoxin family active site.-PS00194,ProSiteProfiles-Thioredoxin domain profile.-PS51352,ProSiteProfiles-PITH domain profile.-PS51532,SUPERFAMILY--SSF49785,SUPERFAMILY--SSF52833

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 283 PF00085: Thioredoxin" amino acids 11 to 102 (92 residues), 88.1 bits, see alignment E=3.5e-29 PF06201: PITH" amino acids 123 to 266 (144 residues), 140.2 bits, see alignment E=6.6e-45

Best Hits

Swiss-Prot: 40% identical to TXL1_SCHPO: Thioredoxin-like protein 1 (txl1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: None (inferred from 42% identity to spu:581305)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (283 amino acids)

>mRNA_487 HMMPfam-Thioredoxin-PF00085,HMMPfam-PITH domain-PF06201,PRINTS-Thioredoxin family signature-PR00421,ProSitePatterns-Thioredoxin family active site.-PS00194,ProSiteProfiles-Thioredoxin domain profile.-PS51352,ProSiteProfiles-PITH domain profile.-PS51532,SUPERFAMILY--SSF49785,SUPERFAMILY--SSF52833 (Rhodosporidium toruloides IFO0880)
MSITVVSSLQQLDSLTSDANKVSIIDFHAVWCGPCKAIAPVFQRLASQYAGRVQFLKVDV
DAVPDVARKFSVSAMPTFVVLKGPNKVDEMKGANPAGLMAMVSKHAPASGGAGASGSGAP
TSLNSQIDLSQIHCLNEAAGHTIKDLLRGSGDKWLESDADEQLLLHIPIQQSIKLRAIRF
TTLSSHSANAPKTIKLFVNQSGVDFDNAESTEAAQEVVLDEAQAKGEKSVELRFVRFQNV
GHLSIFVVDNQGGEDVTRIDKLELIGVSVEGTNMADLKKMEEE