Protein Info for mRNA_510 in Rhodosporidium toruloides IFO0880

Name: 8878
Annotation: K01922 PPCS, coaB phosphopantothenate-cysteine ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04127: DFP
  • amino acids 242 to 334 (93 residues), 40.9 bits, E=1e-14

Predicted SEED Role

"Phosphopantothenoylcysteine synthetase (EC 6.3.2.5)" in subsystem Coenzyme A Biosynthesis (EC 6.3.2.5)

MetaCyc Pathways

• superpathway of coenzyme A biosynthesis I (bacteria) (7/9 steps found)
• superpathway of coenzyme A biosynthesis III (mammals) (4/5 steps found)
• coenzyme A biosynthesis I (prokaryotic) (3/4 steps found)
• coenzyme A biosynthesis II (eukaryotic) (3/4 steps found)
• taurine biosynthesis II (2/4 steps found)

KEGG Metabolic Maps

• Pantothenate and CoA biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.2.5

Protein Sequence (381 amino acids)

>mRNA_510 K01922 PPCS, coaB phosphopantothenate-cysteine ligase (Rhodosporidium toruloides IFO0880)
MSTHTQFSAEDFFAQQPPPKDLDKRLEAVQRFVERNVNEGRRVVLITSGGTTVPLEHNVV
RFLDNFSAGTRGAASAEHFLGSGRYAVIFLHRQHSLQPFSRHYSHSTNPFLDLLDVVEAD
GGVLGKGKAPAEHLPLPDGHLFPPIPSMQSPPSSPPLAYTPLPPLNADEPPNTDHGLTIQ
IRPPHLAPMLSLLRSYKVVKSLGILHSIPYTTVSEYLWYLRGISRVMGQTKDRQGQALGR
RGMYYLAAAVSDFFIPYTKMSEHKIQSGKGSLVIEMDQVPKVLKTMVDEWSNEGFIVSFK
LETDPSILIPKARTALERYGHQIVIGNLLDTRKHEVVFVQKDGEEWLRIPHHDGPDGKEI
EEDIIARLMELHEAWTSKGGV