Protein Info for mRNA_574 in Rhodosporidium toruloides IFO0880

Name: 8942
Annotation: K02999 RPA1, POLR1A DNA-directed RNA polymerase I subunit RPA1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1700 1782 PF04997: RNA_pol_Rpb1_1" amino acids 10 to 281 (272 residues), 79.2 bits, see alignment E=9.3e-26 PF00623: RNA_pol_Rpb1_2" amino acids 544 to 741 (198 residues), 219.4 bits, see alignment E=9e-69 PF04983: RNA_pol_Rpb1_3" amino acids 745 to 922 (178 residues), 115.7 bits, see alignment E=5e-37 PF05000: RNA_pol_Rpb1_4" amino acids 991 to 1074 (84 residues), 77.8 bits, see alignment 1.5e-25 PF04998: RNA_pol_Rpb1_5" amino acids 1081 to 1726 (646 residues), 301.1 bits, see alignment E=2e-93

Best Hits

Predicted SEED Role

"DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6)" in subsystem RNA polymerase I (EC 2.7.7.6)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.6

Use Curated BLAST to search for 2.7.7.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1782 amino acids)

>mRNA_574 K02999 RPA1, POLR1A DNA-directed RNA polymerase I subunit RPA1 (Rhodosporidium toruloides IFO0880)
MDIANPVASQVTSLSFSYLHAPDVRRMSVKQVVNPVLFDNLNNPNAGGLYDPAFGPLGKG
DICSTCHLTSFECPGHFGHIELPAPVFHPLYMVQAFQLLRGTCTYCHRFLVGEVQLLKQI
ARLTLLEHGLVTHALELDAHFQGPAPASKSKSAAAAKARAAAAADNVEDAEQGESTDETA
DEFRARLDAFVQGALRAAKKGKGVGLEHHGRDEYKESGTAFDVRRKVIAQFLKTLGAKRR
CEHCGAYAHRVRKEGHTKIIQYSLVAKQKAIHKTMRLKAPNVLREARLAGFKADGNGKAK
MEVDGETDESEDDSEEEEDKEMDVDGADEADEREEEEEEDDEEAIGSVRGKQTERIVTPD
EVRAHLRRLFANEQELVTLIYAPHGPLARASSSRIPRSSADQKQGGKPAASADIFFMDVV
SVPPSRFRPASTMGDQVFENPQNSLLNNILRQSIVVRDLNVRLLQAQTQPDHPDLVGEDG
KPRVTIERMTTMLYESLIDLQVTVNSMMDAGKNPMLVKQGKLPTPGVKQLLEKKEGLFRK
NMMGKRVNYAARSVISPDVNIETNEIGVPPVFARKLTFPEPVTDHNYQQLKQAVINGPHQ
HPGASFVQMEDGNLISLDRMSLEERTAIANKLLAPETSTAGQRLAASSRPDVGLPPTRTP
QINRKVYRHLQDGDIVILNRQPTLHKPSMMCHRVKVLKGEKTIRMHYANCNSYNADFDGD
EMNMHFPQSLIAQAEARMIANTDNQYLVPTSGNPLRGLIQDHVVAGVWLTNKDTFFTRDQ
YYQLIYGALRPENDYTGEGTVKTVPPAVWKPRPMWTGKQVISTVLKNIQPADMCGIHFTS
KGKVPGSAWGVFAEEGEVLVHDGDMLTGIIDKAQIGASPFGLVHSVYELYGASTAGKLLS
ILSRLLTKFLQTRAFSCRMDDLVLTAKGNHDRRRMLQTVNEKGLSAALDYTGLASADRAD
PATADDLRNRLEEILRDDYKLAGLDATVEGETNQVTTQLIKTCLPNGLVKPFPHNNMQTM
TVSGAKGSNVNASQISCLLGQQSLEGRRVPVMVSGKTLPSFKAFETAPRAGGFVAGRFLT
GIRPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLIKHLEGLRVHYDHTVRNADQSVLQF
HYGEDSLDVTKQKHLLQFEFAVRNMQSIISRYNPRDALERTNDVEEVLPDAMKKSLKKPD
THPPVLSLASPSTVSGAVSERYARAIEEYVKNPKQRLLRPKKKRDMADWPAHIRRDDLVS
IEHFRSLMNMRYMRSLVEPGEAVGLLASQGVGEPSTQMTLNTFHFAGHGAANVTLGIPRL
REIVMTASQDIKTPTMNLPIVESVSDARLKTFCQSSTRLTLSQVVDDVTVEERLTPKTSN
NSYTRSKLYTVRLNLFPRADYEAEYSVSSEQILAGIARTFVPLLDKAIAKEIKQNDRELK
SQAADVGRGKKEGKRRGGKTSGADEDGAGEEDAGVVGRDDGEVIDGDADDERRGRQADDE
QNYDDEDEGDEAADPEEELEAKFKSDAEEDEESSDEEDDDPEAVARRSKAESLERMKQYE
RRVSGSSRFINKLVFDKENGESCEFELEFSSQAAKLLLVGIVEEVCRIAVVHEVPGISRG
FVAKAANANAAAQRNAVTEGVNLRQLWQIGYGIVDLNKLGTNDIGAILRTYGVEAARTAI
INEMSAVFSVYGIGVDYRHLTIIADYMTCEGGYKPFNRTGLGNNASPLTKASYETTSAFI
AEAALHGDFDNMISPSSRIVVGRPPEAGTGAFAIRSIVEAAA