Protein Info for mRNA_595 in Rhodosporidium toruloides IFO0880

Name: 8963
Annotation: KOG0137 Very-long-chain acyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 532 PF00173: Cyt-b5" amino acids 30 to 99 (70 residues), 74.3 bits, see alignment E=1.8e-24 PF02771: Acyl-CoA_dh_N" amino acids 136 to 259 (124 residues), 48.4 bits, see alignment E=3.5e-16 PF02770: Acyl-CoA_dh_M" amino acids 264 to 354 (91 residues), 62.5 bits, see alignment E=8.7e-21 PF00441: Acyl-CoA_dh_1" amino acids 366 to 521 (156 residues), 105.9 bits, see alignment E=5.9e-34 PF08028: Acyl-CoA_dh_2" amino acids 395 to 489 (95 residues), 23.3 bits, see alignment E=1.7e-08

Best Hits

KEGG orthology group: None (inferred from 63% identity to cne:CNB01650)

Predicted SEED Role

"Butyryl-CoA dehydrogenase (EC 1.3.99.2)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases or Butanol Biosynthesis or Isobutyryl-CoA to Propionyl-CoA Module or Isoleucine degradation or Valine degradation (EC 1.3.99.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.2

Use Curated BLAST to search for 1.3.99.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (532 amino acids)

>mRNA_595 KOG0137 Very-long-chain acyl-CoA dehydrogenase (Rhodosporidium toruloides IFO0880)
MAAIAPPSKTKYLTVPETATKKDQLKVFSKDEVAKHNKEDDLWIIVDGAVYDLSKFVDLH
PGGAHVLVQVAGKDATEAFFGMHRSDVLIKYGRYVIGTVEGQKPRVILPTPGTLSPVPYA
EPSWLSEGYYSPYYKDSHRSLQKFMRKFVDEEVKDDANMHELDGKRPTVELIQKMGKLHI
NAMRMGPTKLLHGLTLPGDVKGDEFDYFHELIVTQELSRIGARGYADGLQGGMVIGLPPV
MNFGSDKLKKEIIPDVLAGKKWICLAITEAFAGSDVAGLRTTAKKTPDGKHYIVNGTKKW
ITNGHFADYFSTAVNTGNGLSMLLIPRGEGVETKQIKTSYSTTAGTAYVTFDNVKVPVEN
LLGKEGKGLFVVLSNFNHERWVMCCGSVAGSRMIAEECMKWAHQRRAFGKPLITQAVIRA
KLASMFAKIEALQAYLENLTFQMTHMTYAQQADILAGPIGLLKAQCTRVAGEIADDAVQI
LGGRGITQGGMGVYVERFQRTQKFDAILGGAEEVLFDLGVRQASRKMPQAVL