Protein Info for mRNA_641 in Rhodosporidium toruloides IFO0880

Name: 9009
Annotation: K08333 PIK3R4, VPS15 phosphoinositide-3-kinase, regulatory subunit 4

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1696 transmembrane" amino acids 1335 to 1357 (23 residues), see Phobius details PF07714: Pkinase_Tyr" amino acids 38 to 306 (269 residues), 30.9 bits, see alignment E=4.3e-11 PF00069: Pkinase" amino acids 42 to 308 (267 residues), 66.5 bits, see alignment E=6.5e-22 PF00400: WD40" amino acids 1166 to 1203 (38 residues), 26.8 bits, see alignment (E = 1.8e-09)

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1696 amino acids)

>mRNA_641 K08333 PIK3R4, VPS15 phosphoinositide-3-kinase, regulatory subunit 4 (Rhodosporidium toruloides IFO0880)
MGAAVSQPQSALTAAASAGKAQPGADPFFAELGGEVHYDRSMGSSRFLKAVRGRHRQGAL
VVKVFVKQDPSISLKPFVRRLKAEREALADCPNVQAYGRAIETERAGYLMRQWVASNLYD
RISTRPFLSSVEKRWIAFQLLTGLKHARERGISHGDIKTENVVVTSWNWVYLTDFSSAFK
PTHLPLDDPSEFSFYFDTSSRRTCYIAPERFYSSDSDIAKTKESLEIGKRDGKITEAMDV
FSLGCVLAELWMEGTPPFTLSQLFKYRQGEYSLESYLAEIEDIEIRSLIRSMVSLDPSSR
LSFSDYLNQYRGTAFPEIFYTFLHPFLSALTDSASSSAPPPVPNRPGTATPVTGDGAGLA
ARQEHTLLRTDADDKIERVWTEWEIVARYLDETLPNEDLQKGAESSDERQKNRLPAETFF
PIRLHLPGQEGNVVASGASHDGPALVILALVCANIRNCVRPASVLRALEILLALNRYLTD
ETRLDRLVPYLVTLLSDDAATVRAMALRVLTQTLMLVTTLTPSNVDVFPEYIFPNVRPLA
NDVDILPRETYALCITPLARTARRFLDLAEALKTEGAFELTGLQDFESSPYTGNFDSRLQ
ELHALVQEHIGPLLTDPSTAVKRALLSNIGDLCDFFGRLKANDAVLAHLVTYLNTRDWLL
RKAWNEHAVDVAQCVGPRSLEEYILPLITLSLADPEEFVVVQVLESLTSLASQRLLTKGK
IWELVSPVVSFLCHPNIWIREGSALFLSTVASLLEPTDKWCILYPTIKRLLRSDVKEITA
LSLLDNAREPISRVVFEAAVAWAGKNGKSHFWSATKGPAKGAPRDAGVRTDEDHAQLERL
RQLGMSVEDEYKLTAMRDYIAKVASSRQAMPSRGFYSPDALTPSSSTANLQDLGIVPQTI
FFSVRSPEEMLNVARSRLQGETLSRRFSSTSATSSPRASASLDLNRPVGSRTVSGQPIED
LRRRLAAGAVTKSDSPASPASIQDGADSDSTAHAPTPKADRLDLHRTVSNASTDASEATT
ATTATSSSTVPKVRSRIRLNAVEVGKVTAAVAEDSTNAMGLFDVDARYRASAGDGDSVAG
DAVSQAPTPIEKGGPAKQLPLPQRLVSTYEGNDPNIKQLLERTYLDSYREPLPELGPHVP
PGIPRRKALRTNFPPRERTPNRPEGTLIAHLVEHTDAIVSIQVSPDQLFFVTGSLDGTVK
VWDAMRLEKNVTSKSRQTFQQGGKITSVCFLDNSHCIASASTNGSIWIHRVDVSLSGQMP
RYSKPQLIRQSTVDDGGHATCLASYNTDTSTNLVFGTSLSSIVVLDIRTMRAEHEFANAR
HFGPITALCLDRKHLWLVSGTASGVLSVWDLRFGLLLRSWNIGPRRIHQIAVHPVKGKGR
WIVVAAEPDDGSSPASSSDPSKPRRSSTASTAPLPGTTVAEVWDIDRGHKVDEFRIVSPQ
QQSAQSTALANRPNVFANGAPATSSVSMQDASLDPAAAIEALLAASTAPQSTPPAKSSEA
GRQVVPPIQPTVRAFLLGTDYSMQATTRPAASHLVALQDQQDGYGREAAAKGAGGKDKDG
GFLITGGEDRKLRFWDLGRVSRSAVVSGLGIDEEVPTFSTHTSTVRPSSQADPIQCTIHL
ESTAAPPSASSSQPSSSRPSRPPAPTARVHRSTLIANSQQQLLRAHQEAITAVNVLDLPF
RCVVSGDRAGVVRVFE