Protein Info for mRNA_716 in Rhodosporidium toruloides IFO0880

Name: 9084
Annotation: K01663 HIS7 glutamine amidotransferase / cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 620 TIGR01855: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit" amino acids 4 to 208 (205 residues), 177.6 bits, see alignment E=1.3e-56 PF00117: GATase" amino acids 4 to 197 (194 residues), 66.7 bits, see alignment E=5.1e-22 PF01174: SNO" amino acids 10 to 108 (99 residues), 25.9 bits, see alignment E=1.6e-09 PF07685: GATase_3" amino acids 25 to 191 (167 residues), 32.6 bits, see alignment E=1.3e-11 PF00977: His_biosynth" amino acids 322 to 600 (279 residues), 141.9 bits, see alignment E=4.6e-45

Best Hits

Predicted SEED Role

"Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) / Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)" in subsystem Histidine Biosynthesis (EC 2.4.2.-, EC 4.1.3.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.2.-

Use Curated BLAST to search for 2.4.2.- or 4.1.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (620 amino acids)

>mRNA_716 K01663 HIS7 glutamine amidotransferase / cyclase (Rhodosporidium toruloides IFO0880)
MLYLLDYGAGNVASLANSVRSLGYEFKWVQSAEDIEKADRILFPGVGAFGSAMAGLRKRG
FVEPLKAYIASGRPYMGICIGMQALFASSLESPDEPGLGVIDAQVGRFSSEDKKVPCMGW
NGATERREIGQEGKEAYGFGEGEESYYFVHSYRVDANQPGVQDWALTLTQYGEEKYVSSV
QRGNVFGTQFHPEKGGKAGLAVVEAWLKATDKDGKGMLDVSKKALRPQADVDADLTRKGF
TKRIVACLDVRANDQGDLVVTKGDQYDVREAEESVTTEDVESKPSGAPEESSSTSPSAPV
AETTLPTSTVSSDPTAPPPAKRQRQVRNLGKPVDLARRYYAEGADEVAFLNITSFRSCPL
HDQPMLDVIRQAAETVFVPLTIGGGIRDTTDPDGTTRSALEVAGTYFRCGADKVSIGSDA
VFAVEELLAADGKPTGKTSIETISYAYGAQAVVVSFDPKRVYVNSIDEIPEAHRPCAVDL
AGPLASSPDKELKPDLGPNGERYCWYQCTVRGGRETRDVDVVQLAQGVEKLGAGEILLNS
VDKDGSKSGFDCRLVDLVRRSVGIPVVASSGAGKVEDFSEVFETTGVEAALAAGIFHRKE
VLIEAVKKHLVDAGIKTRRV