Protein Info for mRNA_722 in Rhodosporidium toruloides IFO0880

Name: 9090
Annotation: HMMPfam-Thiopurine S-methyltransferase (TPMT)-PF05724,ProSiteProfiles-Thiopurine or thiol or thiocyanate S-methyltransferase (TPMT) family profile.-PS51585,SUPERFAMILY--SSF53335

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 PF05724: TPMT" amino acids 31 to 211 (181 residues), 107.5 bits, see alignment E=2.1e-34 PF13649: Methyltransf_25" amino acids 78 to 175 (98 residues), 43.5 bits, see alignment E=1.1e-14 PF08241: Methyltransf_11" amino acids 79 to 179 (101 residues), 41.7 bits, see alignment E=3.7e-14 PF08242: Methyltransf_12" amino acids 80 to 177 (98 residues), 31.4 bits, see alignment E=6.6e-11 PF13847: Methyltransf_31" amino acids 80 to 177 (98 residues), 33.9 bits, see alignment E=6.7e-12

Best Hits

KEGG orthology group: None (inferred from 39% identity to cci:CC1G_15733)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (237 amino acids)

>mRNA_722 HMMPfam-Thiopurine S-methyltransferase (TPMT)-PF05724,ProSiteProfiles-Thiopurine or thiol or thiocyanate S-methyltransferase (TPMT) family profile.-PS51585,SUPERFAMILY--SSF53335 (Rhodosporidium toruloides IFO0880)
MAFSRPMQPTEALLKVRQFLKEDPTEGQSATGGWDQAWKAETTPWDAGDVQPAFRELLDE
KWSEVGVSLDELKDGKALVAGCGRGCDAAFIAAHGIDTLGIDLSPTAVEVAKKHLASQPN
APTNITFEAADFFSFPLPSSKPFSFAFDYTFFCALPPSWREKWGNRYAEVVRPGGLLVCL
AFPIDGDREGGPPYSVSEEAYDRVLLPHFGKVYSKQPTRMAEGREPGRDRMIVYRRK