Protein Info for mRNA_777 in Rhodosporidium toruloides IFO0880

Name: 9145
Annotation: KOG0054 Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1312 transmembrane" amino acids 162 to 179 (18 residues), see Phobius details amino acids 258 to 275 (18 residues), see Phobius details amino acids 281 to 298 (18 residues), see Phobius details amino acids 360 to 382 (23 residues), see Phobius details amino acids 389 to 408 (20 residues), see Phobius details amino acids 730 to 749 (20 residues), see Phobius details amino acids 774 to 801 (28 residues), see Phobius details amino acids 813 to 831 (19 residues), see Phobius details amino acids 850 to 878 (29 residues), see Phobius details amino acids 957 to 976 (20 residues), see Phobius details amino acids 982 to 984 (3 residues), see Phobius details amino acids 989 to 1002 (14 residues), see Phobius details PF00664: ABC_membrane" amino acids 234 to 408 (175 residues), 56.4 bits, see alignment E=7.5e-19 amino acids 735 to 976 (242 residues), 97.1 bits, see alignment E=3e-31 PF00005: ABC_tran" amino acids 473 to 604 (132 residues), 51.2 bits, see alignment E=3.9e-17 amino acids 1061 to 1222 (162 residues), 98.7 bits, see alignment E=8.7e-32

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1312 amino acids)

>mRNA_777 KOG0054 Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily (Rhodosporidium toruloides IFO0880)
MPLSPPLDIAIRAERAEAGKKISETSRPRSPEDSNTVLGAFTYSWMSGIMQVAKSRSLRP
TDVWSLSLNNRAEVLARRFASLRSKTLTRKLLRASARDILIDASLKLVASTSEYLRPYFI
QKILENLTLAYTGSPAPESTFSSFLLASITPDSPPWTPREKAYLYTFLAFLSALVKTLAQ
QRHFHYARRIGMRLRSELTVALFEKALKRREKAGIEEKKAEDGSAEEPEQSAASVGKVIT
MISEDVNRVLRMGCDSHLLYGAPLEIALGLIFLYNLMGWSALVGFSLLALSVPINYWLGK
VAVARERQTARDARQTALQELINDVRTVKLFGWSAAFIHRVETKRKVELEWLVRDWFIRY
AYTLLWASMSLLVPLLAFWSYVKLQGEELTVAVAFTALSLFSLVRGPLNQIPGFGIRILQ
LRVSISRMESFFAEEEVDHHVSNGDETAASVVKLEHATLRYAGAKGDRATLVDLDVDFPQ
RQLTVVSGPTGSGKSLLLLGVLGELEVVSGKVVLSPAVSYAAQHPWLESLTVRENIVFGY
PTDEERYRAVIRACALEKDLELLPDGDRTFVGERGISLSGGQKARLALARAVYAPTAVIL
LDDVFAAVDAHVARHLLTHLFAGPLIRDRTCILVTHHVDLVLPLAAYHVQLENGKVIVQG
PVESTQMQSVDAVEEELKGLPDGEGEGAGAAEQTESDAKKERVTAGKAEDWTSGAVKSEM
YKAYLRSSGYTAWVLVLLTVVGRPVFTFLEQFVLRQWGEAATQQDGTVDTNHYLLLYGVV
GAGTSILIVLTAVFISLASLLASRSLFHQLLARVVYAPLRWFDLVPLGTIVNRFTQDIGV
VDDGLAVTMMAFLIAALVVISVVLPVALGTSLIFALIYSTIFRSYLLVNRDVNRIAATTA
SPLFASFAEALRGITTIRAFGKQKEYRARLCNIVDETLAFWYCSATLDIWLSIRTQFLSA
FCLLTTAIFATFFRISPGLAGIAITSSQGVLQALDFLCSAYGRLVLSMNSLERITEYLEV
PQEPQGGVIPPANWPSLTFLSSCVADQPLAHRYDTNLPPVLHGVSFSVMAGERVGIVGRT
GSGKSTLATSLLRFRDPASGSVVVDGLDISHVSLEELRKRITLVPQEATLFEGTLRDNLD
PFDEHTDAECIAALKRAHLLDPDVMEADDGGEGGRAKPTSTMSLDLAVAAGGANWSAGQR
QLIALARALLRDSRIVILDESSASLDHALDTKLQQVIRKEFKDAAVLTIAHRLRHTVCSS
LCARRRTVIDYDRILVLDAGRIVELESPDKLLAKEDGVFKRLWDESQGGTKA