Protein Info for mRNA_894 in Rhodosporidium toruloides IFO0880

Name: 9262
Annotation: K01694 TRP tryptophan synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 704 PF00290: Trp_syntA" amino acids 9 to 264 (256 residues), 283.7 bits, see alignment E=9.4e-89 TIGR00262: tryptophan synthase, alpha subunit" amino acids 11 to 264 (254 residues), 225.7 bits, see alignment E=4.5e-71 TIGR00263: tryptophan synthase, beta subunit" amino acids 300 to 681 (382 residues), 607.2 bits, see alignment E=1.3e-186 PF00291: PALP" amino acids 347 to 670 (324 residues), 170.8 bits, see alignment E=4.9e-54

Best Hits

KEGG orthology group: K01694, tryptophan synthase [EC: 4.2.1.20] (inferred from 65% identity to mgl:MGL_0012)

Predicted SEED Role

"Tryptophan synthase beta chain (EC 4.2.1.20)" in subsystem Auxin biosynthesis or Tryptophan synthesis (EC 4.2.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (704 amino acids)

>mRNA_894 K01694 TRP tryptophan synthase (Rhodosporidium toruloides IFO0880)
MSQHLRDTFAAKEDSNSPAFVTFLTAGFPTVDATVPLMLAMERGGADIIELGVPFTDPLA
DGKAIQECNNIALDQGVDYTRCLEFVKEARSQGLKTPVILMGYFNPLLAHGEEKAVQDAK
SAGANGFIIVDLPPEEAVNFRKICTREGMSYVPLIAPSTSTERIKFLASIADSFIYVVSK
MGTTGASDKVSSSLSAMLSRIRGLLNRPIPLAVGFGVSTREHFEEVGRDADGVVIGSQLV
AIIKDSFQLGQAAAVSAVEAYCQQVSGNRTRAAPLPKRAVSADDKAKEIASVEEKVAKAA
RFGDFGGAYVPEALYDALEELTTAYADARADPEFWKEWEGEFGYINRPSQLYEARRLTEH
CGGAKIWFKREDLNHTGSHKINNAIGQILIARRLGKTRIIAETGAGQHGVATATACAKFG
LECVVYMGEEDVRRQSLNVFRMRMLGAKVVAVASGTKTLKDAINEAMRDWVTNLSSTHYL
VGSAIGPAPFPTIVRDFQSVIGTEIKEQLKAATGRLPDAVVACVGGGSNAIGTFHPFIND
TSVRIVGVEAAGEGVDTERHSATISRGTKGVFHGVRTYILQTKVGQILGTHSISAGLDYP
GVGPEHAWLHETKRGEYISATDEEALRGFRACTQMEGIIPALETSHAVWATMQLAKTMPK
EANIVMTLSGRGDKDVQEISEILPGKWADKLDWHIDSNANTVQG