Protein Info for mRNA_1009 in Rhodosporidium toruloides IFO0880

Name: 9377
Annotation: K12659 ARG56 N-acetyl-gamma-glutamyl-phosphate reductase / acetylglutamate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00761: acetylglutamate kinase
  • amino acids 106 to 332 (227 residues), 195.6 bits, E=8.7e-62
• PF00696: AA_kinase
  • amino acids 107 to 324 (218 residues), 83.5 bits, E=2.9e-27
• PF04768: NAT
  • amino acids 341 to 508 (168 residues), 147 bits, E=6.5e-47
• TIGR01850: N-acetyl-gamma-glutamyl-phosphate reductase
  • amino acids 574 to 906 (333 residues), 276.1 bits, E=4.6e-86
• PF01118: Semialdhyde_dh
  • amino acids 574 to 701 (128 residues), 95.8 bits, E=3.9e-31

Predicted SEED Role

"Acetylglutamate kinase (EC 2.7.2.8) / N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38)" in subsystem Arginine Biosynthesis extended (EC 1.2.1.38, EC 2.7.2.8)

MetaCyc Pathways

• L-arginine biosynthesis II (acetyl cycle) (9/9 steps found)
• L-arginine biosynthesis I (via L-ornithine) (8/9 steps found)
• superpathway of arginine and polyamine biosynthesis (13/17 steps found)
• L-arginine biosynthesis III (via N-acetyl-L-citrulline) (7/9 steps found)
• L-ornithine biosynthesis I (4/5 steps found)
• L-arginine biosynthesis IV (archaea) (6/9 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.2.1.38 or 2.7.2.8

Protein Sequence (909 amino acids)

>mRNA_1009 K12659 ARG56 N-acetyl-gamma-glutamyl-phosphate reductase / acetylglutamate kinase (Rhodosporidium toruloides IFO0880)
MLAAATRQGAQLGRALRNQPAKACRSLSSSTVSPSSLLLQSQRRVEQQQQRASDELGDIA
VKRWLGHAAANGTDADRETIVRLLYSLASRREVSRYLQIFSSATHFAVLKVGGAILTNDL
ESLTLSLNFLHRVGLYPVVVHGMGDKLNARLEADGIVPDYIDGIRITDARTLSHARRVFL
SENLKLVSALEALGTRARPITTGVFTAEYLDKPRYGFVGRITGVDKEPIEASIRAGALPI
LTSLAETPDGQILNVNADVATAELAKVLEPLKIVYLSEKGGLFHGVTKEKISLINLDEEY
DDLMKQEWVKYGTKLKLREIKDLLDHLPRSSSVAIIQPDNLQKELFTDSGAGTLLRRGYK
LYKHASIDAVGQDRLRRVLSERDEDVTSGRKSVAQVLSELEKQQAPFTIYGDEPCDVVAI
VSHPEGQTPVMTKFLANQTAIQNGVTDNVFNSIKRDFKRLFWTAKADDENKSWHFERADG
SFTRNGRSLYYYGVQDAGEVERLVKDLDASQRIERAYLPISYTSSARGTVHSEPKLASAL
RSYSTSARRPAPTAFGQQTRSFSTSPAYAAAAKRVALIGARGYTGQNLVSLLNTHPSLSL
SHCSSRELAGQPLSDYTKDKVTYQNLSFKEIEQLEAQSAVDAWVMALPNGVMAPFVEAID
KGAQGKSDEKKSVVIDLGADKRFDDSWTYGLPELYGRDALRTAKRISNPGCFATVMQMLA
APLIPHMSAPPTVFAVSGFSGAGTKSGSEPKIPAESLKGGIRPYALTDHIHEREAAFQLS
KLVTDEAQLSKDELKPAFIPSVAPWFQGIIATISVPLKQEMRASQVKELFEQKYAGEKLV
KLQNEVPEIYQIAGKHGVRIGGIQVHSSGKRVVIVGVIDNLLKGAATQCLQNLNIALGCD
ELEGIPLDF