Protein Info for mRNA_1067 in Rhodosporidium toruloides IFO0880

Name: 9435
Annotation: K01580 E4.1.1.15, gadB, gadA, GAD glutamate decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 561 TIGR01788: glutamate decarboxylase" amino acids 51 to 508 (458 residues), 546.9 bits, see alignment E=1.5e-168 PF00282: Pyridoxal_deC" amino acids 78 to 405 (328 residues), 214.1 bits, see alignment E=1.4e-67

Best Hits

KEGG orthology group: K01580, glutamate decarboxylase [EC: 4.1.1.15] (inferred from 53% identity to mgl:MGL_4226)

Predicted SEED Role

"Glutamate decarboxylase (EC 4.1.1.15)" in subsystem Acid resistance mechanisms (EC 4.1.1.15)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.15

Use Curated BLAST to search for 4.1.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (561 amino acids)

>mRNA_1067 K01580 E4.1.1.15, gadB, gadA, GAD glutamate decarboxylase (Rhodosporidium toruloides IFO0880)
MSLSRHLNPDRVIQEAREHSKKHRGGRETIHDMLNRGEASGHLHGSHKGHANYDTDPIPK
YRIPSKGTDAKTAYDLVNSELLLDGNPQLNLASFVHTQMSEYADRIMFENRMKNQIDSDE
YPGTTLIHNRLVSMIASLWHADDKKEDATGCVTTGSSEAAQLGGLAMKKMWQARRKAAGK
SWKEPGPNIVLGSNAQVALEKFARYFDVEARFVDVDESTKYVMDPKRAVELVDENTIGVY
VILGSTYTGTYENVEEMSRLLDEYEAKTGHYVPIHVDAASGGFVAPFASPSLKWDFRIPR
VVSINSSGHKFGQSYVGCGFIVWRDKQHLPKELVFELHYLGSVEYSFSLNFSRPAAPFLA
QYFNLLYLGFEGYRRVALNDLKNARLLARALERSKYYKVVSEVHHLKDRSLTEKAKETVG
AVDDVEAYVPSLPVVAFMFSDEFRKEYPRIKQRSIQLGLREHNWIVPNYDLPPNAQDKEV
LRVVIRENFNEDMVERLFHDIIEVTEQLMDEHKADVRQPGEGEGRNVNAPKHGKGKEQSV
SERMAASHGEGTRPVGHDSVC