Protein Info for mRNA_1076 in Rhodosporidium toruloides IFO0880

Name: 9444
Annotation: K02324 POLE1 DNA polymerase epsilon subunit 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 200 400 600 800 1000 1200 1400 1600 1800 2000 2246 PF03104: DNA_pol_B_exo1" amino acids 110 to 466 (357 residues), 268.4 bits, see alignment E=2.4e-83 PF10108: DNA_pol_B_exo2" amino acids 376 to 514 (139 residues), 34.1 bits, see alignment 5.9e-12 PF00136: DNA_pol_B" amino acids 818 to 1181 (364 residues), 35.7 bits, see alignment E=1.1e-12 PF08490: DUF1744" amino acids 1535 to 1927 (393 residues), 451.6 bits, see alignment E=5e-139

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (2246 amino acids)

>mRNA_1076 K02324 POLE1 DNA polymerase epsilon subunit 1 (Rhodosporidium toruloides IFO0880)
MGRPFNKFSRGRGGGGQSSGRSGGSWRGRRGGGRGGGAAGAGQLKTVTEGTRDDDRIEDA
RVWDELDHKLGFAKFQEGAKRQGWLVNMKETLVPDETKTSARAGVDYYFIQDDGGMFKAT
LAYEPYFYIATRSGYEGVVEEWLMRKYEDLITKVSRVRKEDLKLPNHLMGYRRDYISLSF
RNQTDLFTVRRDLLPLATKNREMLDAVDTYAEVVAGEQKFGQVGMEYDMEDGFGGEGFVK
NVGGAGGKGANAMDPKDAIIDIREYDVPYYLRVAIDKNIRVGLWYEVTADAGEISFRLLE
ERVARAEPVVMAFDIETTKAPLKFPDQLTDQVMMISYMIDGQGFLITNREIVGADIEDFE
YTPKPDYEGPFTIFNEADEAATILRFFEHFREARPTVCATYNGDSFDFPFLLARANVHGI
DMYKEIGFAKDSEEEFKSRSCVHMDCFRWVKRDSYLPQGSQGLKAVTVAKLGYNPIELDP
ELMTPYAADQPQTLAQYSVSDAVATYYLYMKYVHPFVFSLCNIIPLNPDEVLRKGSGTLC
ETLLMVEAYRSNVVYPNRHVESHNNMYDGHLLESETYVGGHVEALEAGVFRSDIETDFKI
VPSAIQELIDDLDDALKFALAKEGKKPIPIEDVENYDEVKGEIIRMLEELRDRPLRADTP
LIYHLDVAAMYPNIMLSNRLQPDSVVTEADCAACDFNRPGKQCQRRMKWAWRGEYFPAQL
NEYKMIRNALEQETFPPKWPGKPERRFTELSPSEQTSLLHKRLGDYSRKVYAKTKETKIE
TKEAIICQRENPFYIDTVRTFRDRRYTYKGLHKDWKKKLDQASGGGGVQEIVEAKAMIVL
YDSLQLAHKCILNSFYGYVMRKGARWHSMEMAGITCLTGASIIQMARKLVEQIGRPLELD
TDGIWCMLPSTFPDGFAFKLRGGGKFPISYPCTMLNHIVHKDFTNDQYHEATPDGRHVVR
EENSIFFELDGPYRAMILPSSKEEDKLLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKT
FQSQIFEKFLLGGTLKDCYAAVATVADKWLDVLFTKAVSLPDDELVELIAENRSMSKTLA
EYAGQKSTSISTARRLAEFLGEQMVKDKGLACKFIISTKPVGAPVTERAVPVAIFSAELS
VKRHFLRKWLKDNALEEFDLRSILDWDYYIERLGSVVQKLITIPAALQKIPNPVPRIRHP
DWLHRRVANQDDKIKQHRVDEMFARQKPAIRDVEDIGSKEVIIVTPREPTPPPPAVPKPD
IMKTYSAWVAYMKPIWREKRKELLASQKSSSGFGGRAGTLGSMMHQRSTFLSSAVWDIVQ
ITPVSDRPGEFKMWLLIADSLQSVRLRIPRQFFVNFVELPTADGVFPEACEVEPISRSLP
RGQRSLNLVRLSTSEDDFVRDEPLYGELLNGPNVDGVYELQVPLVMRALLRLGSSCIPDS
RKGVTLNKGLDRYFALDDLKPAEATLSKRRYLDLGRNLRYTYLFHVTNDYRHVFGLFMPT
GTAKVYVVERGKARDVQNLDKYYEEQLKKRKEAEAERLKKDKSAKREVGAFEYADRMTMI
VAYASNEDVALRHLSRDLDALSKQKSMASLLVVHSPKPRSYFDEKVRGAANFPLIAIQSS
KAENTFPTALAWQAPACRRMIQHYLRAAVWIRERIELADRFDVPVCNLEKDVPLFLADID
FARRLSKADCVLWWSPAARPDLGGREADANASQLGDELINPELGKPGCYSNACLEVEVRN
LAVDAVLQSALVYELEGGEGGGIDEAAHNLDDYAKGTAHAPHVLGDAILPTSTFNMVRAM
VKAWSVEAAKPDGAHWRLMLDHFWRWTSSPAAKLYDPALYRFVHGLMRKTFSQLLAEFRR
LGSDIVHADFGRIFLLTSKPSSSTAYAYANYLVSSVTTRELFRYVQLEIVRFWDQLVWMD
AANSAGIVCPRPDLDEQPLDQVEVEMQFNVATYLPDAVQDDFTKVIGRFVHGMLVAKRQQ
SADLRTPLRILQNGLETVERGKAIGDKDGDDDAKSPANTLISETLTRQFLKAVTRLKDAY
ADKEDPEAFDFPELPGSHLRPKNPVLEFIKTTCAVLALAKDVSEEVVILKRNLLDLIGVR
EFAKEAIFVNPCLPFKVPMVVCRSCNSIRDLDLCRNVAFLVKDQPWLCERCSTEYDRAAI
EALIIDSLQRRLVSYQLQDLRCGKCKTMKSENLRSHCDCSGEYQMSETRQDLVKRLQVTS
KVADFHNLQVLATAVEWMQDLLHWCA