Protein Info for mRNA_1102 in Rhodosporidium toruloides IFO0880

Name: 9470
Annotation: K03327 TC.MATE, SLC47A, norM, mdtK, dinF multidrug resistance protein, MATE family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 612 transmembrane" amino acids 143 to 167 (25 residues), see Phobius details amino acids 188 to 205 (18 residues), see Phobius details amino acids 220 to 240 (21 residues), see Phobius details amino acids 257 to 277 (21 residues), see Phobius details amino acids 289 to 311 (23 residues), see Phobius details amino acids 323 to 347 (25 residues), see Phobius details amino acids 367 to 386 (20 residues), see Phobius details amino acids 414 to 435 (22 residues), see Phobius details amino acids 447 to 467 (21 residues), see Phobius details amino acids 480 to 501 (22 residues), see Phobius details amino acids 543 to 562 (20 residues), see Phobius details amino acids 568 to 588 (21 residues), see Phobius details PF01554: MatE" amino acids 149 to 310 (162 residues), 98.5 bits, see alignment E=1.7e-32 amino acids 381 to 520 (140 residues), 78.1 bits, see alignment E=3.2e-26 TIGR00797: MATE efflux family protein" amino acids 158 to 520 (363 residues), 209.3 bits, see alignment E=4.4e-66

Best Hits

Predicted SEED Role

"Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (612 amino acids)

>mRNA_1102 K03327 TC.MATE, SLC47A, norM, mdtK, dinF multidrug resistance protein, MATE family (Rhodosporidium toruloides IFO0880)
MARGQTSLSGPAAPSTTGEAAAAAEGQGARLGKRRSTGRLSRSSVSMEGRLSPTEESVDE
EALADEFDEAAETDRLLPDQPQRLQPPAHATLPYRPVTESTPLLGHSATTDGFTTPAEEE
AIERARKLDEKARFAMYSEAKTLFGYSVPILGTHFLEYSLLATVVLATGHLGETELAAAS
LGNLTNNVASLSIIQGLCAALDTLCPQAFSSSRPQDTSIYAIRTWLICLALVIPQGIFFF
NSEWILRDGLRQDPDVAYYAAQYLKILTFASPAYSGFECIRRWLQAQGLMVAPVLALIAA
APINILLNWILVVGPFDSLRLGFIGAPIATTISINVMFLVMLVYSILRAPREAWSGFTRE
TFTGFGLNIRLGLAGIGMVGSEWWSWEIVGLATSFLGPTALAAQSVLLTSASLFYQYQYA
LSVAAAVRIGNLLGAQKPSLARVASRVTIFIAIVVSGLNSIMLVLLRNVWGHLFSSDKEI
IVLVADVLPIVAAFQLCDGLSGAMGGVLRGAGKPTLGAIVRPHPAPPPRDSRSPCRCAQI
NTSSYYIIGLPIGIALSFAGPHLGLNGLWIGLTVALTFTGLSSTYIVWKMDWEGEAEATR
VRLGEAKRDEEQ