Protein Info for mRNA_1254 in Rhodosporidium toruloides IFO0880

Name: 9622
Annotation: K02150 ATPeV1E, ATP6E V-type H+-transporting ATPase subunit E

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 223 PF01991: vATP-synt_E" amino acids 19 to 213 (195 residues), 185.5 bits, see alignment E=3.9e-59

Best Hits

Swiss-Prot: 46% identical to VATE_NEUCR: V-type proton ATPase subunit E (vma-4) from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)

KEGG orthology group: K02150, V-type H+-transporting ATPase subunit E [EC: 3.6.3.14] (inferred from 54% identity to uma:UM03951.1)

MetaCyc: 42% identical to H+-translocating V-ATPase subunit E1 (Homo sapiens)
ATPSYN-RXN [EC: 7.1.2.2]

Predicted SEED Role

No annotation

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14 or 7.1.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (223 amino acids)

>mRNA_1254 K02150 ATPeV1E, ATP6E V-type H+-transporting ATPase subunit E (Rhodosporidium toruloides IFO0880)
MPGLTDDEVVSEMRKMTAFIKQEALEKAREIKVKADEEFAIEKGKIVRQESANIDANFER
KKKQAEIEKKIAISNQNNKARLQLLEKREELLEKVFDEAKAKIGDATKDQSKYAELLRNL
VLQALFRLMEKNVKVSGRPKDQEILKKAVDDAASEFKEKSGIDVRVEVDDQLSDKSNGGI
ILTGARITVNNTLDERLRLLSELALPALRENLFGKNPNRAFFS