Protein Info for mRNA_1332 in Rhodosporidium toruloides IFO0880

Name: 9700
Annotation: K00232 E1.3.3.6, ACOX1, ACOX3 acyl-CoA oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF14749: Acyl-CoA_ox_N
  • amino acids 30 to 134 (105 residues), 25.9 bits, E=2.6e-09
• PF02770: Acyl-CoA_dh_M
  • amino acids 145 to 255 (111 residues), 68.5 bits, E=9.8e-23
• PF00441: Acyl-CoA_dh_1
  • amino acids 286 to 456 (171 residues), 30.9 bits, E=6e-11
• PF01756: ACOX
  • amino acids 496 to 678 (183 residues), 173.4 bits, E=7.4e-55

Best Hits

KEGG orthology group: K00232, acyl-CoA oxidase [EC: 1.3.3.6] (inferred from 59% identity to cne:CNG00320)

Predicted SEED Role

No annotation

MetaCyc Pathways

• superpathway of glyoxylate cycle and fatty acid degradation (13/14 steps found)
• fatty acid β-oxidation II (plant peroxisome) (4/5 steps found)
• (5Z)-dodecenoate biosynthesis II (4/6 steps found)
• methyl ketone biosynthesis (engineered) (4/6 steps found)
• propanoyl-CoA degradation II (3/5 steps found)
• fatty acid β-oxidation VI (mammalian peroxisome) (4/7 steps found)
• fatty acid β-oxidation V (unsaturated, odd number, di-isomerase-dependent) (2/5 steps found)
• fatty acid β-oxidation VII (yeast peroxisome) (2/5 steps found)
• oleate β-oxidation (isomerase-dependent, yeast) (1/4 steps found)
• 6-gingerol analog biosynthesis (engineered) (2/6 steps found)
• 9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast) (3/10 steps found)
• (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase) (4/13 steps found)
• 10-cis-heptadecenoyl-CoA degradation (yeast) (3/12 steps found)
• 10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast) (3/12 steps found)
• docosahexaenoate biosynthesis III (6-desaturase, mammals) (4/14 steps found)
• jasmonic acid biosynthesis (7/19 steps found)
• crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered) (2/14 steps found)

KEGG Metabolic Maps

• Biosynthesis of plant hormones
• Biosynthesis of unsaturated fatty acids
• Fatty acid metabolism
• alpha-Linolenic acid metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.3.3.6

Use Curated BLAST to search for 1.3.3.6

Protein Sequence (728 amino acids)

>mRNA_1332 K00232 E1.3.3.6, ACOX1, ACOX3 acyl-CoA oxidase (Rhodosporidium toruloides IFO0880)
MPTPLADTPTPPTPMETIAKERLNPPFDLRRMTYAMGDGEKEVKLREKHMMEIQRNPLFR
LDDIHDLTKDQLRERTMAKFSTMVSYVSNERIDEFQKRMNVVSLADPGFWTRFVILGAIR
SGATANQMSYWMSKGLLGLNGMVGCFGMTELAHGSNVAGLETTATFDEQTDEFVIHTPSV
SATKWWIGGAAHSATHCSVFAQLIVKGQVYGTKTFIVPLREPKTYQLLPGVAIGDIGKKM
GRDGIDNGWIQFTNVRIPRAYMLMKHTQVTRDGEVREPPLAQLTYGALLQGRTAMVADAA
NVAKKALTIAIRYAAVRRQFKVGENKLESQLLDYPIHQRRLLPLLSQAVAMGFTSYRMTA
LFEEMSGQLESLGSDSDEAETKEVLEKLKETHATSAGLKAFCTWNALETIEKCRASLGGH
GYSAYSGLPGMYADQAVQCTWEGDNTILTLQSGRSLVSSYADAVKGQKLPGGTAYLNGLP
GVLTASCPSDEATLDLKTLEAGWDTVSANVVRQAYEKFEGAMKSGKGREEALELCSQERF
VAARVHTAGYMFRMFHEALVELAKDEPKDNGVIKTLDDICRLYGCWAIEENAAQFLKYKF
FTPKQMDIISNEVTSLCAELRKCAVLLTDSFGFTDHIINSPFGRYDGNVYESYYNQVKAA
NPHNPVAPYFERVIRPLIEREPLELGDDADSMELDDEIAEIQAEREEEKGEAETADEAEK
ELKKPAEE