Protein Info for mRNA_1337 in Rhodosporidium toruloides IFO0880

Name: 9705
Annotation: K17732 PMPCB, MAS1 mitochondrial-processing peptidase subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 PF00675: Peptidase_M16" amino acids 41 to 188 (148 residues), 172.1 bits, see alignment E=7.9e-55 PF05193: Peptidase_M16_C" amino acids 193 to 382 (190 residues), 125.5 bits, see alignment E=2.6e-40

Best Hits

Swiss-Prot: 74% identical to MPPB_LENED: Mitochondrial-processing peptidase subunit beta (mppB) from Lentinula edodes

KEGG orthology group: K01412, mitochondrial processing peptidase [EC: 3.4.24.64] (inferred from 75% identity to lbc:LACBIDRAFT_292439)

MetaCyc: 52% identical to cytochrome bc1 complex mitochondrial processing peptidase beta-subunit (Arabidopsis thaliana col)

Predicted SEED Role

"Ubiquinol-cytochrome C reductase complex core protein I, mitochondrial precursor (EC 1.10.2.2)" in subsystem Ubiquinone Menaquinone-cytochrome c reductase complexes (EC 1.10.2.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.10.2.2

Use Curated BLAST to search for 1.10.2.2 or 3.4.24.64

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (467 amino acids)

>mRNA_1337 K17732 PMPCB, MAS1 mitochondrial-processing peptidase subunit beta (Rhodosporidium toruloides IFO0880)
MLARNLLRTARRAPAPFQRTLATHASSPLTQISTLPNGLTVATEASPSASTATVGVWIDA
GSRAETDKTSGTAHFLEHMAFKGTGKRSQHQLELEVENLGAHLNAYTSREQTVYYAKSFA
SDVNKSVEIIADILTGSKLESGAIERERDVILREQQEVDKQLEEVVFDHLHAVAFQGQPL
GRTILGPKENILSIQRDDLASYIKKNYTADRMVLVGTGGVEHSSLVDLANKHFGSLSSSP
EPIKLGASSAKTKPDFIGSEVRVRDDTMPTCNVAIAVEGVGWQSPDYYTMLVMQSIMGNW
DRSLGAQSLLSSRLSHIISSNNLANSFMSFSTSYSDTGLWGCYLVSENVTNLDDLTHFLM
KEWCRLSTHPTDGEVARAKAQLKASLLLGLDGTTAVAEDIGRQLVTTGRRNTPKEIEAAV
DAVTTADVMRCAKKYLWDKDIAVAAVGRVEGLLDYSRMRAGMTSLMW