Protein Info for mRNA_1340 in Rhodosporidium toruloides IFO0880

Name: 9708
Annotation: KOG3968 Atrazine chlorohydrolase/guanine deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01979: Amidohydro_1
  • amino acids 76 to 476 (401 residues), 173.9 bits, E=5.9e-55
• PF07969: Amidohydro_3
  • amino acids 239 to 417 (179 residues), 32.7 bits, E=6.1e-12

Predicted SEED Role

"Guanine deaminase (EC 3.5.4.3)" in subsystem Purine Utilization or Purine conversions (EC 3.5.4.3)

MetaCyc Pathways

• purine nucleotides degradation II (aerobic) (11/11 steps found)
• purine nucleotides degradation I (plants) (11/12 steps found)
• guanosine nucleotides degradation II (4/4 steps found)
• guanosine nucleotides degradation III (4/4 steps found)
• superpathway of purines degradation in plants (14/18 steps found)
• superpathway of guanosine nucleotides degradation (plants) (5/6 steps found)
• drosopterin and aurodrosopterin biosynthesis (4/7 steps found)
• purine nucleobases degradation II (anaerobic) (14/24 steps found)
• purine nucleobases degradation I (anaerobic) (5/15 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.5.4.3

Use Curated BLAST to search for 3.5.4.3

Protein Sequence (483 amino acids)

>mRNA_1340 KOG3968 Atrazine chlorohydrolase/guanine deaminase (Rhodosporidium toruloides IFO0880)
MLDPVDISLVLRGTVVSSRPDRSLSIREDCLVAVDSKGFIAAIDDGTGSALADEVDTLVR
EGKVGDDKVVELGDGWVLPGFVDTHIHAPQYPNAGMALDKPLMEWLEAYTFAAESRIDKD
PAHAQRVYQKLVQRLLENGTTAASVFGTISVEANLTLAKAFLDAGIRGQIGKVAMDQNSL
PSYIETTDSSLSDTHRFIESIHSLVASSPHDQQIVEPVVTPRFVPTCSIKLMKGLSQLAK
EKGVRIQSHMCESQGMVDVCREILGGKSDVQVLDELGLLNNRSLMAHCTHSSADDLSRLS
RTGTAIASCPLSNVYFSAERQLPLREAWDAGVKVGLGSDISGGYRVGIDENMRWAVGVSR
LREGERQRDLRAGSREDERSSSLAITWKEALYLATLGGAQALGLDEERKVGALEVGSAFD
AQWIQLGHPRSRVDWFDDEEEGGVIKRVSTEEKLEKWFCNGSEVDRKAVWVQGKRVYSRP
ETW