Protein Info for mRNA_1349 in Rhodosporidium toruloides IFO0880

Name: 9717
Annotation: K12852 EFTUD2 116 kDa U5 small nuclear ribonucleoprotein component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 980 PF16004: EFTUD2" amino acids 2 to 117 (116 residues), 121.7 bits, see alignment E=8.2e-39 PF00009: GTP_EFTU" amino acids 139 to 448 (310 residues), 160.6 bits, see alignment E=1.1e-50 TIGR00231: small GTP-binding protein domain" amino acids 141 to 272 (132 residues), 59.6 bits, see alignment E=1.7e-20 PF01926: MMR_HSR1" amino acids 142 to 269 (128 residues), 28.6 bits, see alignment E=3.9e-10 PF03144: GTP_EFTU_D2" amino acids 501 to 574 (74 residues), 39.8 bits, see alignment 1.5e-13 PF03764: EFG_IV" amino acids 717 to 833 (117 residues), 82.2 bits, see alignment E=8.1e-27 PF00679: EFG_C" amino acids 837 to 924 (88 residues), 70.5 bits, see alignment E=3.1e-23

Best Hits

Swiss-Prot: 59% identical to U5S1_MOUSE: 116 kDa U5 small nuclear ribonucleoprotein component (Eftud2) from Mus musculus

KEGG orthology group: K12852, 116 kDa U5 small nuclear ribonucleoprotein component (inferred from 65% identity to cci:CC1G_13743)

Predicted SEED Role

"Translation elongation factor 2" in subsystem Translation elongation factor G family or Translation elongation factors eukaryotic and archaeal or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (980 amino acids)

>mRNA_1349 K12852 EFTUD2 116 kDa U5 small nuclear ribonucleoprotein component (Rhodosporidium toruloides IFO0880)
MDLYDEFGNYIGPEDDLESDYSDDEAGEQQQQDGAASPAPAPLRAYDEDEAEPLEGMEVD
DVPSSNAIVLHEDKTYYASASATYGPGVETMVQEEDAQPLSVPIIEPVKTRKFRLGARTG
PERRWDDQFMMGLASNPETVRNVAIVGHLHHGKTSLVDMLVTETHKIDIDADKQLRFTDT
HSLSQSRKISIKSSPMSLVLSNTKGKSYLVNLVDTPGHSNFVDEIASAVRVADGAVVVVD
AVEGVMLTTTQTIQHLVKNRIPIVLVVNKVDRLILELRLPPGDAYFKLKQTIEEVNTVIS
ELDPDPALRVSPERGNVAFASTQMGWCFTLKSFAKMYADTYGPMDLDQFAVRLWGNIYYH
PETRKFSRQSAPGAKRGFEHFIMEPLYKLYSQVIGEDTDSLRKTLHQLGIHFKPSVYKMD
VRPLLRLVLAHFFGPPTGFVDMLVQHVPNPQQGARVKVESTYTGALDSPLGQALLNCDPE
GPLAIQIVKLYPTPDASEFRAFGRVLSGTAQVGQEVKVLGEGYSPEDEEDMIVQQIGGIY
VGEARYDIETDAMPAGNFVQLSGVDNSISKTATLIAADYDASELRIFRPIAHFTQSVLKV
SVEPLMPSELPKMLDGLRKVNKTYPLIETRVEESGEHVLLGTGELYLDCAMHDLRVMFAE
IEIKISDPVVRFCETVVETSALKCYADTPNKKNKITMIAEPLERGIAEDIETGKISIRLP
PKQLGQHFQNKYGWDLLASRSIWAFGPDDQGPNLLMDDTLPSDVDKKLLYTVKESIKQGF
QWGCREGPLCDEPIRNVKFRLLGADLAQEPIYRGGGQIIPTARRVCYSSFLMATPRLQEP
VYFVEIQAPQDCVPAIYEILARRRGHVTKDIPKPGSPLFTVQAYIPVVDANGFETDLRTH
TLGQAFCVQTFDHWSICPGDPLDKTIQLRPLEPAPAQALARDFVLKTRRRKGLNDQVNVA
KFLEAEMVTLLASTEHLDLL