Protein Info for mRNA_1470 in Rhodosporidium toruloides IFO0880
Name: 9838
Annotation: K18592 GGT1_5, CD224 gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Gamma-glutamyltranspeptidase (EC 2.3.2.2)" in subsystem Glutathione: Biosynthesis and gamma-glutamyl cycle or Utilization of glutathione as a sulphur source (EC 2.3.2.2)
MetaCyc Pathways
- γ-glutamyl cycle (5/6 steps found)
- glutathione degradation (DUG pathway - yeast) (2/2 steps found)
- leukotriene biosynthesis (1/6 steps found)
- hypoglycin biosynthesis (4/14 steps found)
KEGG Metabolic Maps
- Arachidonic acid metabolism
- Cyanoamino acid metabolism
- Glutathione metabolism
- Selenoamino acid metabolism
- Taurine and hypotaurine metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.3.2.2
Use Curated BLAST to search for 2.3.2.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (634 amino acids)
>mRNA_1470 K18592 GGT1_5, CD224 gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase (Rhodosporidium toruloides IFO0880) MTHLPPPKPGARNPSYLVSGWNGAVASEEERCSRMGVDVLRENGTAVDAAITTALCIGVV NSFSSGIGGGGFMVIRPPSSTRHGLPSTYDTLRNPHCTHPISVDFRETAPLASHPDMFTA SARPDDPSWDPNRASKVGGLAVGVPGELRGFQAAYEACGGGVSWERIFRPVAQLAREFRV GKELHRRLNARWSGGDEGPTISEWIKDEEDWRAMFMRPGGNEFLQEGDIVRREAYARTLE KLGKGGADVFYEGEIADRIVETVRKDGGILSKDDMRSYKAIVRRAEEGTYRGRKYYTGSY PSGGPIIRMLFNVLDGYADFVDAGRTGLAEHRFIEAMKFAFAARTNVGDPPFIDNAAKLA EIPTRKYADAVRGNITDSRTHKLSYYHPRFDIKEDHGTTHLSVIDQWGGAVALTTTVNLI FGSRLMDEETGIILNDEMDDFATPGLPDAFGLRPSPFNYPVGGKRPLSSTAPLIMDHANS DDVYLSLGGSGGSRIFGAVAQTLLNLDWGHDLSSAVEAPRVHHQLLPAYVSIESTFRPDL VKELKARGHDVTLFDINLGIAEVQAVMRDRDGRFFGAFKRRTLALRKPTQADLIPFAAAS DSRKNGCVLSPSPAMRASIANRVLHEQGPCSILE