Protein Info for mRNA_1488 in Rhodosporidium toruloides IFO0880
Name: 9856
Annotation: K15371 GDH2 glutamate dehydrogenase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00260, glutamate dehydrogenase [EC: 1.4.1.2] (inferred from 53% identity to cpw:CPC735_053720)Predicted SEED Role
"NAD-specific glutamate dehydrogenase (EC 1.4.1.2), eukaryotic type" in subsystem Glutamate dehydrogenases or Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 1.4.1.2)
MetaCyc Pathways
- L-glutamate degradation I (1/1 steps found)
- L-alanine degradation II (to D-lactate) (2/3 steps found)
- ethene biosynthesis IV (engineered) (1/3 steps found)
- L-glutamate degradation V (via hydroxyglutarate) (5/10 steps found)
- 4-aminobutanoate degradation V (2/7 steps found)
- L-glutamate degradation XI (reductive Stickland reaction) (2/7 steps found)
- methylaspartate cycle (9/19 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.4.1.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (1043 amino acids)
>mRNA_1488 K15371 GDH2 glutamate dehydrogenase (Rhodosporidium toruloides IFO0880) MPSAMLSPPSPLEHLKDRLDVPRTPSPAHGTIKHNDLGYRKASFAGKDKHKEAVVDIVAS NGFLPELLVQPEVDWFYSQLGIDDGYFSLTSPQEVADHVESLYGAKVQAHASHQDYLEIK LEKEGDSSAVYIFTSPPGVSLANGPQYEQRIDSQYLDNSNPTDAWRLESYRAVPPATTNG DDTNGQAPIESVAAQLRSYFVSKCDFVDTKLDEQELVKPGVNIREVGDKTFLEKATDNTL EIYQELMDEALRRMGPVVAAYDVENSRERRIVLAYKQGGTRSFFSALSDLYHSYGFYSTR KYVENLRNGVTIISLYLHPLQGIPNEGNILQIIKESSLIYVLPNNPLFTGSQLSVQESTY AYSAWVFAQHFLNRLGPSYAALKNILDENDSVQAGVLSDIRARFRQETFTRASILECLQQ YPDVIRLAYISFAYTHYYSNYGNNLVPTLSYARLQTAEVLTSDQLKAHIRKNVLNKHDAQ ILESLVTFNNAILKTNFFTSTKVALSFRLDPDFLPESEYPVRAYGLFLVVGDGFRGFHLR FKDVARGGLRMIMSRNREAYSVNQRSLFDEVYGLASTQALKNKDIPEGGSKGAILPDLGA NPQTCFCKFVDSIFDLLLPGRTPGVKDKIIDLYGKEEILFFGPDEGTANYMAWVADHARA RGAPWWKASSTGKPASTHGGIPHDIYGMTSLSVRGYTTGIYRKLGLKEEEITKVQTGGPD GDLGSNEILLSKDKTITIIDGSGTLHDPHGINREELVRLAKARKMVVNFDRSKLSKDGYL ILVDDRDVTLPNGDVVADGTDFRNTAHLHYKADILVPCGGRPESVNVNNVSKLWDADGVT NFKYIVEGANLFITQGARLQLEKKGVVLFRDASANKGGVTSSSLEVLSGMALDDAQFIDL MTSAGKDGLPEFYQQYARSIQETIFKNATAEFETIWAAHEKTGRPFTLLSDDLSRKLVQL QAEMEESTLYDDQQMRRAVMERALPKLLIDTAGLDKILARLPEAYKHSVFSCYVASHFVY TYGIDASPIDFYRFLRSLTQDDN