Protein Info for mRNA_1492 in Rhodosporidium toruloides IFO0880

Name: 9860
Annotation: K12855 PRPF6, PRP6 pre-mRNA-processing factor 6

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF06424: PRP1_N
  • amino acids 19 to 150 (132 residues), 155.6 bits, E=2.6e-49
• PF14559: TPR_19
  • amino acids 587 to 636 (50 residues), 31.3 bits, 4.8e-11

Best Hits

Swiss-Prot: 47% identical to PRP1_SCHPO: Pre-mRNA-splicing factor prp1 (prp1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K12855, pre-mRNA-processing factor 6 (inferred from 60% identity to lbc:LACBIDRAFT_323426)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

• lactose degradation III (1/1 steps found)
• lactose degradation II (1/3 steps found)
• xyloglucan degradation II (exoglucanase) (3/8 steps found)

KEGG Metabolic Maps

• Galactose metabolism
• Glycosaminoglycan degradation
• Glycosphingolipid biosynthesis - ganglio series
• Other glycan degradation
• Sphingolipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Protein Sequence (906 amino acids)

>mRNA_1492 K12855 PRPF6, PRP6 pre-mRNA-processing factor 6 (Rhodosporidium toruloides IFO0880)
MADIFGLRGERYAFLRLAPPPSYVAGAGRGAQGFTTRSDIGPAREQVQEDEGPKEEEYNP
DQFQDPENETGLFAGTVYEADDEEADRIYEAVDAKIDERRRARREQREREEAEQLLKDRP
TIQSQFADLKRGLADMSEDDWYNLPEVSNMIGNRVKKPRLEGRSYVVPDSVIVGNRDKGA
LESALAEEQMKDGFQTPADALTDFAEIGQAREKMLSIKLEQAGTDSALGSTNIDPKGYLT
GLDSQLLKTSSEIGDIKRARALLQSLTKTNPKHAPGWVAAAWLENVAGKQVAARKIIAEG
CEQCPKNEDVWLCASELNTNENAKIILANAVQELPQSVRIWMRAVELEHDVKAKKRVLRK
ALEYIPASVKLWKETVKLEENPDDARILLARAVEVIPHSQELWLALARLETPERARAVLN
KARKAIPTSHEIWIAAGRLQEQEGNVAQVDAIIATGVASLKKNQAELSREQWLAEAERAE
QQGSTVTAQAIVKATIHLDVDEEDRQAVWMDDAETMTNKGMIATARAIYAYALNVFPQKQ
SIWRKAADLEKHHGDRETLLALLNRAVESVPQAEVLWLMAAKESWLSGDVDGARQILSRA
FEANPDSEGIWLAAVKLEAENGQIEAAKQLMQRAREVSGTERIWVKSAVFERTHSENAAA
LQMVKDGLKVYPASAKLHMMQAQLLQAQTPPNLAAAREALAAGVRKCPTSVPLWIMASRL
EEQAGVRIKARALLEKARNVNPKSDELWLESVKVEERDGSGAAKPMLARALQTLPASGLL
HSYSVWQEPRPTRKTRSVDALKKTNNAPAVIVTVARLFWGERKVEKARDWFGRAVAADGD
YGDAWAWWWKFEKQHGTDEHRQLLLEKCIAADPHHGHVWPAIAKDPKNVGKNIKAILDLT
ADALEA