Experiment setAAux_DOC for Rhodosporidium toruloides IFO0880

Compare to:

Dropout Complete

200 most detrimental genes:

  gene name fitness t score description  
mRNA_6775 15143 +3.0 1.5 K14784 CMS1 protein CMS1 compare
mRNA_4670 13038 +2.8 2.4 Hypothetical Protein compare
mRNA_3203 11571 +2.3 1.9 Hypothetical Protein compare
mRNA_2185 10553 +2.3 3.2 HMMPfam-Copper fist DNA binding domain-PF00649,PRINTS-Copper fist domain signature-PR00617,ProSiteProfiles-Copper-fist DNA-binding domain profile.-PS50073,SMART-Copper-Fist-SM00412,SMART--SM01090,SUPERFAMILY--SSF57879 compare
mRNA_2748 11116 +2.2 2.3 KOG3772 M-phase inducer phosphatase compare
mRNA_5386 13754 +2.2 2.1 Hypothetical Protein compare
mRNA_4878 13246 +2.1 12.2 K04348 PPP3C, CNA serine/threonine-protein phosphatase 2B catalytic subunit compare
mRNA_1969 10337 +2.0 2.3 K14961 RBBP5, SWD1, CPS50 COMPASS component SWD1 compare
mRNA_109 8477 +2.0 1.6 Hypothetical Protein compare
mRNA_7792 16160 +2.0 0.9 Hypothetical Protein compare
mRNA_699 9067 +2.0 5.1 K20289 COG2 conserved oligomeric Golgi complex subunit 2 compare
mRNA_3307 11675 +1.9 10.8 K06268 PPP3R, CNB serine/threonine-protein phosphatase 2B regulatory subunit compare
mRNA_1538 9906 +1.9 1.8 K20307 TRAPPC10, TRS130 trafficking protein particle complex subunit 10 compare
mRNA_7419 15787 +1.9 1.2 Hypothetical Protein compare
mRNA_374 8742 +1.9 1.5 Hypothetical Protein compare
mRNA_1261 9629 +1.9 1.1 K04712 DEGS sphingolipid Delta-4 desaturase compare
mRNA_7448 15816 +1.8 1.2 BLAST putative protein of unknown function [Pseudozyma ... compare
mRNA_1755 10123 +1.8 8.6 K00326 E1.6.2.2 cytochrome-b5 reductase compare
mRNA_3988 12356 +1.8 0.7 Hypothetical Protein compare
mRNA_2364 10732 +1.8 3.0 K20471 COPD, ARCN1, RET2 coatomer subunit delta compare
mRNA_6799 15167 +1.8 0.5 K00033 PGD, gnd, gntZ 6-phosphogluconate dehydrogenase compare
mRNA_327 8695 +1.7 1.3 KOG0378 40S ribosomal protein S4 compare
mRNA_1480 9848 +1.7 0.8 KOG0254 Predicted transporter (major facilitator superfamily) compare
mRNA_3664 12032 +1.7 0.9 K15111 SLC25A26 solute carrier family 25 (mitochondrial S-adenosylmethionine transporter), member 26 compare
mRNA_7666 16034 +1.7 1.2 K20184 VPS41 vacuolar protein sorting-associated protein 41 compare
mRNA_1290 9658 +1.7 1.5 K03872 TCEB1 transcription elongation factor B, polypeptide 1 compare
mRNA_4065 12433 +1.7 2.9 KOG1198 Zinc-binding oxidoreductase compare
mRNA_6268 14636 +1.6 1.2 HMMPfam-Survival motor neuron protein (SMN)-PF06003 compare
mRNA_7424 15792 +1.6 1.4 Hypothetical Protein compare
mRNA_2270 10638 +1.6 6.5 K19833 CLA4 serine/threonine-protein kinase CLA4 compare
mRNA_5369 13737 +1.5 1.0 K03627 MBF1 putative transcription factor compare
mRNA_6411 14779 +1.5 1.1 BLAST proteophosphoglycan ppg4 [Moniliophthora roreri M... compare
mRNA_118 8486 +1.5 0.9 HMMPfam-Protein of unknown function (DUF1674)-PF07896 compare
mRNA_7823 16191 +1.5 0.7 K03011 RPB3, POLR2C DNA-directed RNA polymerase II subunit RPB3 compare
mRNA_5624 13992 +1.5 1.4 KOG1611 Predicted short chain-type dehydrogenase compare
mRNA_3819 12187 +1.5 1.4 HMMPfam-MYND finger-PF01753,SUPERFAMILY--SSF144232 compare
mRNA_177 8545 +1.5 1.0 KOG4096 Uncharacterized conserved protein compare
mRNA_8363 16731 +1.5 4.3 KOG1693 emp24/gp25L/p24 family of membrane trafficking proteins compare
mRNA_5805 14173 +1.4 2.7 HMMPfam-Ion transport protein-PF00520,SUPERFAMILY--SSF81324 compare
mRNA_65 8433 +1.4 2.6 K12882 NCBP1, CBP80 nuclear cap-binding protein subunit 1 compare
mRNA_2822 11190 +1.4 0.4 SUPERFAMILY--SSF52047 compare
mRNA_3729 12097 +1.4 6.4 K15280 SLC35C2 solute carrier family 35, member C2 compare
mRNA_2688 11056 +1.4 2.0 Hypothetical Protein compare
mRNA_7169 15537 +1.3 1.3 K13137 STRAP, UNRIP serine-threonine kinase receptor-associated protein compare
mRNA_6839 15207 +1.3 7.8 K17257 ITFG1 integrin alpha FG-GAP repeat containing protein 1 compare
mRNA_6738 15106 +1.3 1.1 Hypothetical Protein compare
mRNA_6224 14592 +1.3 2.1 Hypothetical Protein compare
mRNA_4955 13323 +1.3 1.9 K20306 TRAPPC9, TRS120 trafficking protein particle complex subunit 9 compare
mRNA_6401 14769 +1.3 1.4 HMMPfam-Phosphotransferase enzyme family-PF01636,SUPERFAMILY--SSF56112 compare
mRNA_3015 11383 +1.3 1.2 KOG3252 Uncharacterized conserved protein compare
mRNA_7571 15939 +1.3 0.7 K11450 KDM1A, AOF2, LSD1 lysine-specific histone demethylase 1A compare
mRNA_3624 11992 +1.3 1.1 SUPERFAMILY--SSF52047 compare
mRNA_2386 10754 +1.3 3.7 K01530 E3.6.3.1 phospholipid-translocating ATPase compare
mRNA_2319 10687 +1.3 3.4 KOG3872 FOG FHA domain compare
mRNA_6154 14522 +1.3 14.3 K16667 PTPRG receptor-type tyrosine-protein phosphatase gamma compare
mRNA_70 8438 +1.2 3.3 HMMPfam-Membrane-associating domain-PF01284 compare
mRNA_3516 11884 +1.2 0.9 K01466 allB allantoinase compare
mRNA_5898 14266 +1.2 1.2 Hypothetical Protein compare
mRNA_4968 13336 +1.2 6.7 KOG4464 Signaling protein RIC-8/synembryn (regulates neurotransmitter secretion) compare
mRNA_1211 9579 +1.2 1.7 K15078 SLX1 structure-specific endonuclease subunit SLX1 compare
mRNA_4137 12505 +1.2 8.1 BLAST putative protein [Melanopsichium pennsylvanicum 4] compare
mRNA_5144 13512 +1.2 2.1 BLAST putative mit domain-containing protein [Erysiphe neca... compare
mRNA_3305 11673 +1.2 0.6 KOG3299 Uncharacterized conserved protein compare
mRNA_2189 10557 +1.2 3.7 K11236 CDC24 cell division control protein 24 compare
mRNA_1934 10302 +1.2 6.5 HMMPfam-Cryptococcal mannosyltransferase 1-PF11735 compare
mRNA_7315 15683 +1.2 1.1 K05527 bolA BolA protein compare
mRNA_5734 14102 +1.2 0.6 K01183 E3.2.1.14 chitinase compare
mRNA_3597 11965 +1.2 1.2 K15562 BUR1, SGV1 serine/threonine-protein kinase BUR1 compare
mRNA_486 8854 +1.2 2.1 HMMPfam-Domain of unknown function (DUF202)-PF02656 compare
mRNA_8371 16739 +1.2 0.5 HMMPfam-GPR1/FUN34/yaaH family-PF01184 compare
mRNA_4395 12763 +1.2 1.9 HMMPfam-RTA1 like protein-PF04479 compare
mRNA_8199 16567 +1.1 0.3 Hypothetical Protein compare
mRNA_2097 10465 +1.1 0.3 K03217 yidC, spoIIIJ, OXA1, ccfA YidC/Oxa1 family membrane protein insertase compare
mRNA_1677 10045 +1.1 8.0 K15620 GOLPH3, GPP34 golgi phosphoprotein 3 compare
mRNA_3285 11653 +1.1 3.4 KOG2069 Golgi transport complex subunit compare
mRNA_8159 16527 +1.1 3.3 K17607 TIPRL, TIP41 type 2A phosphatase activator TIP41 compare
mRNA_6819 15187 +1.1 4.5 SUPERFAMILY--SSF103107 compare
mRNA_6301 14669 +1.1 2.6 Hypothetical Protein compare
mRNA_5548 13916 +1.1 1.8 KOG4006 Anti-proliferation factor BTG1/TOB compare
mRNA_988 9356 +1.1 1.5 BLAST glycerol-3-phosphate O-acyltransferase [Sanghuangporu... compare
mRNA_7374 15742 +1.1 1.0 Hypothetical Protein compare
mRNA_7200 15568 +1.1 2.9 K14816 REI1 pre-60S factor REI1 compare
mRNA_942 9310 +1.1 1.6 KOG1743 Ferric reductase-like proteins compare
mRNA_6291 14659 +1.1 3.2 K12182 HGS, HRS, VPS27 hepatocyte growth factor-regulated tyrosine kinase substrate compare
mRNA_2487 10855 +1.1 2.1 BLAST putative protein [Melanopsichium pennsylvanicum 4] compare
mRNA_5616 13984 +1.1 0.6 HMMPfam-GRF zinc finger-PF06839 compare
mRNA_5808 14176 +1.1 1.3 HMMPfam-Cytochrome oxidase complex assembly protein 1-PF08695 compare
mRNA_275 8643 +1.1 0.9 BLAST nitrogen assimilation transcription factor [Rhodo... compare
mRNA_6239 14607 +1.1 2.4 K01372 BLMH, pepC bleomycin hydrolase compare
mRNA_7510 15878 +1.1 5.1 K11644 SIN3A paired amphipathic helix protein Sin3a compare
mRNA_7106 15474 +1.1 2.0 K11313 SUPT3H, SPT3 transcription initiation protein SPT3 compare
mRNA_3302 11670 +1.1 3.2 K07232 chaC cation transport protein ChaC compare
mRNA_2009 10377 +1.1 3.6 BLAST ankyrin [Cenococcum geophilum 1.58] compare
mRNA_2511 10879 +1.1 0.8 Hypothetical Protein compare
mRNA_1982 10350 +1.0 3.4 HMMPfam-Copper binding proteins, plastocyanin/azurin family-PF00127,ProSiteProfiles-Prokaryotic membrane lipoprotein lipid attachment site profile.-PS51257,SUPERFAMILY--SSF49503 compare
mRNA_6917 15285 +1.0 2.0 K04883 KCNAB2 potassium voltage-gated channel Shaker-related subfamily A, beta member 2 compare
mRNA_7336 15704 +1.0 2.2 Hypothetical Protein compare
mRNA_6057 14425 +1.0 2.7 Hypothetical Protein compare
mRNA_3107 11475 +1.0 3.0 K11412 SIRT2, SIR2L2 NAD-dependent deacetylase sirtuin 2 compare
mRNA_6536 14904 +1.0 3.9 HMMPfam-Protein of unknown function (DUF837)-PF05769 compare
mRNA_1946 10314 +1.0 2.1 KOG2458 Endoplasmic reticulum protein EP58, contains filamin rod domain and KDEL motif compare
mRNA_7572 15940 +1.0 0.9 Hypothetical Protein compare
mRNA_7044 15412 +1.0 4.2 KOG4299 PHD Zn-finger protein compare
mRNA_1888 10256 +1.0 1.5 HMMPfam-Protein of unknown function (DUF2423)-PF10338 compare
mRNA_8334 16702 +1.0 5.8 BLAST mtf1_muccl ame full transcription factor mtf1 [Licht... compare
mRNA_5720 14088 +1.0 3.4 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1 compare
mRNA_7116 15484 +1.0 4.3 K04393 CDC42 cell division control protein 42 compare
mRNA_113 8481 +1.0 1.7 KOG0209 P-type ATPase compare
mRNA_6800 15168 +1.0 4.7 K04709 LAG1 Acyl-CoA-dependent ceramide synthase compare
mRNA_3987 12355 +1.0 2.9 K08576 CAPN7 calpain-7 compare
mRNA_7229 15597 +1.0 1.1 Hypothetical Protein compare
mRNA_273 8641 +1.0 2.1 K15174 PAF1 RNA polymerase II-associated factor 1 compare
mRNA_5335 13703 +1.0 1.4 HMMPfam-Domain of unknown function (DUF4202)-PF13875 compare
mRNA_967 9335 +1.0 1.0 HMMPfam-Starch binding domain-PF00686,SUPERFAMILY--SSF49452 compare
mRNA_6489 14857 +1.0 6.6 KOG0327 Translation initiation factor 4F, helicase subunit (eIF-4A) and related helicases compare
mRNA_6876 15244 +1.0 2.2 Hypothetical Protein compare
mRNA_753 9121 +1.0 2.7 K02737 PSMB5 20S proteasome subunit beta 5 compare
mRNA_1260 9628 +1.0 9.3 Hypothetical Protein compare
mRNA_3917 12285 +1.0 1.7 KOG4479 Transcription factor e(y)2 compare
mRNA_2677 11045 +1.0 2.3 ProSitePatterns-Zinc finger C2H2 type domain signature.-PS00028,ProSiteProfiles-Zinc finger C2H2 type domain profile.-PS50157 compare
mRNA_8332 16700 +1.0 4.2 K10082 LMAN2, VIP36 lectin, mannose-binding 2 compare
mRNA_1031 9399 +1.0 2.1 Hypothetical Protein compare
mRNA_3639 12007 +1.0 1.0 K11204 GCLC glutamate--cysteine ligase catalytic subunit compare
mRNA_3777 12145 +1.0 3.4 K20346 TMED4_9_11 p24 family protein alpha compare
mRNA_3201 11569 +1.0 2.4 K12175 GPS1, COPS1, CSN1 COP9 signalosome complex subunit 1 compare
mRNA_1282 9650 +1.0 0.7 Hypothetical Protein compare
mRNA_7078 15446 +1.0 1.0 Hypothetical Protein compare
mRNA_8457 16825 +1.0 1.7 K02728 PSMA4 20S proteasome subunit alpha 3 compare
mRNA_7551 15919 +1.0 5.2 KOG1032 Uncharacterized conserved protein, contains GRAM domain compare
mRNA_182 8550 +1.0 0.0 K19828 MTG1 mitochondrial GTPase 1 compare
mRNA_2905 11273 +1.0 2.6 Hypothetical Protein compare
mRNA_1978 10346 +1.0 6.6 K14409 SMG7, EST1C protein SMG7 compare
mRNA_443 8811 +1.0 1.1 KOG2742 Predicted oxidoreductase compare
mRNA_6513 14881 +1.0 6.3 HMMPfam-Glycosyl transferase family 90-PF05686,SMART-Putative lipopolysaccharide-modifying enzyme.-SM00672 compare
mRNA_7515 15883 +1.0 9.6 K07827 KRAS, KRAS2 GTPase KRas compare
mRNA_5201 13569 +1.0 1.6 K02304 MET8 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase compare
mRNA_1000 9368 +1.0 4.1 BLAST glycosyltransferase 2 [Moniliophthora roreri MCA ... compare
mRNA_4802 13170 +1.0 5.2 K09313 CUTL homeobox protein cut-like compare
mRNA_8067 16435 +1.0 2.4 K12399 AP3S AP-3 complex subunit sigma compare
mRNA_1684 10052 +1.0 1.5 Hypothetical Protein compare
mRNA_1178 9546 +1.0 2.0 Hypothetical Protein compare
mRNA_7417 15785 +1.0 0.5 K03353 APC6, CDC16 anaphase-promoting complex subunit 6 compare
mRNA_3589 11957 +0.9 2.4 HMMPfam-F-box domain-PF00646,ProSiteProfiles-F-box domain profile.-PS50181,SMART-A Receptor for Ubiquitination Targets-SM00256,SUPERFAMILY--SSF101908,SUPERFAMILY--SSF81383 compare
mRNA_5863 14231 +0.9 0.5 K09281 K09281 copper-fist transcription factor compare
mRNA_715 9083 +0.9 3.6 KOG2893 Zn finger protein compare
mRNA_8246 16614 +0.9 0.3 Hypothetical Protein compare
mRNA_6539 14907 +0.9 4.7 K19800 SCH9 serine/threonine protein kinase SCH9 compare
mRNA_6296 14664 +0.9 2.4 Hypothetical Protein compare
mRNA_1806 10174 +0.9 1.3 BLAST related to C2H2 zinc finger protein [Ustilago hordei] compare
mRNA_4080 12448 +0.9 0.9 Hypothetical Protein compare
mRNA_1912 10280 +0.9 5.7 K04450 ATF2, CREBP1 cyclic AMP-dependent transcription factor ATF-2 compare
mRNA_4891 13259 +0.9 1.9 KOG3140 Predicted membrane protein compare
mRNA_8230 16598 +0.9 3.0 K09668 LARGE glycosyltransferase-like protein LARGE compare
mRNA_6322 14690 +0.9 4.9 K09420 MYB myb proto-oncogene protein compare
mRNA_5091 13459 +0.9 2.7 Hypothetical Protein compare
mRNA_7314 15682 +0.9 2.9 Hypothetical Protein compare
mRNA_2798 11166 +0.9 1.2 K03537 POP5 ribonuclease P/MRP protein subunit POP5 compare
mRNA_4213 12581 +0.9 -0.0 K01673 cynT, can carbonic anhydrase compare
mRNA_3890 12258 +0.9 4.1 HMMPfam-Pal1 cell morphology protein-PF08316 compare
mRNA_6221 14589 +0.9 2.5 HMMPfam-BTB/POZ domain-PF00651,ProSiteProfiles-BTB domain profile.-PS50097,SMART-Broad-Complex, Tramtrack and Bric a brac-SM00225,SUPERFAMILY--SSF54695 compare
mRNA_3834 12202 +0.9 1.6 Hypothetical Protein compare
mRNA_8148 16516 +0.9 0.8 HMMPfam-START domain-PF01852,ProSiteProfiles-START domain profile.-PS50848,SUPERFAMILY--SSF55961 compare
mRNA_6369 14737 +0.9 1.9 Hypothetical Protein compare
mRNA_6138 14506 +0.9 1.2 Hypothetical Protein compare
mRNA_8117 16485 +0.9 3.7 K06041 kdsD, kpsF arabinose-5-phosphate isomerase compare
mRNA_8008 16376 +0.9 1.2 BLAST CAMK/CAMKL protein kinase [Microbotryum lychnidis-dio... compare
mRNA_7869 16237 +0.9 1.3 KOG4366 Predicted thioesterase compare
mRNA_5126 13494 +0.9 2.1 Hypothetical Protein compare
mRNA_858 9226 +0.9 0.8 K10599 PRPF19, PRP19 pre-mRNA-processing factor 19 compare
mRNA_2874 11242 +0.9 0.7 K00555 TRMT1, trm1 tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase compare
mRNA_2831 11199 +0.9 2.7 HMMPfam-short chain dehydrogenase-PF00106,PRINTS-Glucose/ribitol dehydrogenase family signature-PR00081,SMART--SM00822,SUPERFAMILY--SSF51735 compare
mRNA_4569 12937 +0.9 1.0 HMMPfam-Integral peroxisomal membrane peroxin-PF06398 compare
mRNA_6346 14714 +0.9 3.4 HMMPfam-Protein of unknown function (DUF938)-PF06080,SUPERFAMILY--SSF53335 compare
mRNA_84 8452 +0.9 1.2 K01522 FHIT bis(5'-adenosyl)-triphosphatase compare
mRNA_6975 15343 +0.9 5.7 Hypothetical Protein compare
mRNA_3254 11622 +0.9 0.8 K12161 URM1 ubiquitin related modifier 1 compare
mRNA_7273 15641 +0.9 4.5 K15859 SKN7 osomolarity two-component system, response regulator SKN7 compare
mRNA_2437 10805 +0.9 4.9 Hypothetical Protein compare
mRNA_1534 9902 +0.8 3.0 K12493 ARFGAP2_3 ADP-ribosylation factor GTPase-activating protein 2/3 compare
mRNA_2368 10736 +0.8 1.9 Hypothetical Protein compare
mRNA_3753 12121 +0.8 5.1 K00728 POMT dolichyl-phosphate-mannose-protein mannosyltransferase compare
mRNA_4571 12939 +0.8 2.8 KOG4419 5' nucleotidase compare
mRNA_5934 14302 +0.8 1.7 HMMPfam-Mitochondrial carrier protein-PF00153,ProSiteProfiles-Solute carrier (Solcar) repeat profile.-PS50920,SUPERFAMILY--SSF103506 compare
mRNA_4743 13111 +0.8 2.6 BLAST Nucleolar protein 4 [Choanephora cucurbitarum] compare
mRNA_1032 9400 +0.8 1.7 Hypothetical Protein compare
mRNA_3626 11994 +0.8 2.3 BLAST SH3 domain-containing protein [Rhizoctonia solani AG-... compare
mRNA_3473 11841 +0.8 4.8 K11578 ZW10, DSL1 protein transport protein DSL1/ZW10 compare
mRNA_6951 15319 +0.8 1.3 ProSiteProfiles-Ribonuclease III family domain profile.-PS50142,SUPERFAMILY--SSF69065 compare
mRNA_7833 16201 +0.8 3.7 HMMPfam-Cryptococcal mannosyltransferase 1-PF11735 compare
mRNA_4321 12689 +0.8 5.3 K14960 CXXC1, SPP1, CPS40 COMPASS component SPP1 compare
mRNA_1692 10060 +0.8 5.4 K20292 COG5 conserved oligomeric Golgi complex subunit 5 compare
mRNA_6825 15193 +0.8 4.2 K08876 SCYL1 SCY1-like protein 1 compare
mRNA_4605 12973 +0.8 1.6 KOG0254 Predicted transporter (major facilitator superfamily) compare
mRNA_3783 12151 +0.8 2.4 KOG1502 Flavonol reductase/cinnamoyl-CoA reductase compare
mRNA_8440 16808 +0.8 0.5 Hypothetical Protein compare
mRNA_2891 11259 +0.8 1.5 Hypothetical Protein compare
mRNA_1484 9852 +0.8 5.6 HMMPfam-Cation efflux family-PF01545,SUPERFAMILY--SSF161111 compare
mRNA_1673 10041 +0.8 1.4 Hypothetical Protein compare
mRNA_1145 9513 +0.8 2.9 K00669 AANAT arylalkylamine N-acetyltransferase compare
mRNA_1055 9423 +0.8 1.4 KOG0590 Checkpoint kinase and related serine/threonine protein kinases compare


Specific Phenotypes

None in this experiment

For Rhodosporidium toruloides IFO0880 in auxotrophy experiments

For auxotrophy unknown across organisms