Experiment setAAux_Met for Rhodosporidium toruloides IFO0880

Compare to:

YNB Glucose 75mM Methionine

200 most detrimental genes:

  gene name fitness t score description  
mRNA_6268 14636 +2.6 2.3 HMMPfam-Survival motor neuron protein (SMN)-PF06003 compare
mRNA_5369 13737 +2.3 1.7 K03627 MBF1 putative transcription factor compare
mRNA_3988 12356 +2.2 1.2 Hypothetical Protein compare
mRNA_4670 13038 +2.2 1.3 Hypothetical Protein compare
mRNA_4213 12581 +2.1 1.2 K01673 cynT, can carbonic anhydrase compare
mRNA_4878 13246 +2.0 15.7 K04348 PPP3C, CNA serine/threonine-protein phosphatase 2B catalytic subunit compare
mRNA_6775 15143 +1.9 1.0 K14784 CMS1 protein CMS1 compare
mRNA_7666 16034 +1.9 1.5 K20184 VPS41 vacuolar protein sorting-associated protein 41 compare
mRNA_699 9067 +1.8 5.6 K20289 COG2 conserved oligomeric Golgi complex subunit 2 compare
mRNA_7419 15787 +1.8 0.8 Hypothetical Protein compare
mRNA_118 8486 +1.8 1.2 HMMPfam-Protein of unknown function (DUF1674)-PF07896 compare
mRNA_2748 11116 +1.8 1.4 KOG3772 M-phase inducer phosphatase compare
mRNA_7823 16191 +1.8 1.3 K03011 RPB3, POLR2C DNA-directed RNA polymerase II subunit RPB3 compare
mRNA_327 8695 +1.8 1.1 KOG0378 40S ribosomal protein S4 compare
mRNA_5616 13984 +1.8 1.7 HMMPfam-GRF zinc finger-PF06839 compare
mRNA_3203 11571 +1.7 1.2 Hypothetical Protein compare
mRNA_2319 10687 +1.7 4.7 KOG3872 FOG FHA domain compare
mRNA_374 8742 +1.7 1.2 Hypothetical Protein compare
mRNA_3305 11673 +1.7 0.7 KOG3299 Uncharacterized conserved protein compare
mRNA_1560 9928 +1.7 2.8 HMMPfam-Bromodomain-PF00439,ProSiteProfiles-Bromodomain profile.-PS50014,SMART-bromo domain-SM00297,SUPERFAMILY--SSF47370 compare
mRNA_4065 12433 +1.7 2.5 KOG1198 Zinc-binding oxidoreductase compare
mRNA_1969 10337 +1.6 1.6 K14961 RBBP5, SWD1, CPS50 COMPASS component SWD1 compare
mRNA_3307 11675 +1.6 9.5 K06268 PPP3R, CNB serine/threonine-protein phosphatase 2B regulatory subunit compare
mRNA_1755 10123 +1.6 7.0 K00326 E1.6.2.2 cytochrome-b5 reductase compare
mRNA_7374 15742 +1.6 1.5 Hypothetical Protein compare
mRNA_1538 9906 +1.5 1.8 K20307 TRAPPC10, TRS130 trafficking protein particle complex subunit 10 compare
mRNA_6738 15106 +1.5 1.5 Hypothetical Protein compare
mRNA_5144 13512 +1.5 2.9 BLAST putative mit domain-containing protein [Erysiphe neca... compare
mRNA_177 8545 +1.5 0.7 KOG4096 Uncharacterized conserved protein compare
mRNA_2185 10553 +1.5 2.4 HMMPfam-Copper fist DNA binding domain-PF00649,PRINTS-Copper fist domain signature-PR00617,ProSiteProfiles-Copper-fist DNA-binding domain profile.-PS50073,SMART-Copper-Fist-SM00412,SMART--SM01090,SUPERFAMILY--SSF57879 compare
mRNA_4891 13259 +1.4 3.5 KOG3140 Predicted membrane protein compare
mRNA_443 8811 +1.4 2.1 KOG2742 Predicted oxidoreductase compare
mRNA_182 8550 +1.4 0.4 K19828 MTG1 mitochondrial GTPase 1 compare
mRNA_4237 12605 +1.4 0.8 K15100 SLC25A1, CTP solute carrier family 25 (mitochondrial citrate transporter), member 1 compare
mRNA_3516 11884 +1.4 0.9 K01466 allB allantoinase compare
mRNA_2364 10732 +1.4 2.3 K20471 COPD, ARCN1, RET2 coatomer subunit delta compare
mRNA_5805 14173 +1.4 2.5 HMMPfam-Ion transport protein-PF00520,SUPERFAMILY--SSF81324 compare
mRNA_5734 14102 +1.4 0.6 K01183 E3.2.1.14 chitinase compare
mRNA_7336 15704 +1.4 3.2 Hypothetical Protein compare
mRNA_3580 11948 +1.4 0.6 KOG0715 Molecular chaperone (DnaJ superfamily) compare
mRNA_2905 11273 +1.4 4.0 Hypothetical Protein compare
mRNA_523 8891 +1.3 2.6 K11644 SIN3A paired amphipathic helix protein Sin3a compare
mRNA_2270 10638 +1.3 5.7 K19833 CLA4 serine/threonine-protein kinase CLA4 compare
mRNA_6281 14649 +1.3 1.8 HMMPfam-Stress responsive A/B Barrel Domain-PF07876,ProSiteProfiles-Stress-response A/B barrel domain profile.-PS51502,SMART-Stress responsive A/B Barrel Domain-SM00886,SUPERFAMILY--SSF54909 compare
mRNA_2386 10754 +1.3 4.6 K01530 E3.6.3.1 phospholipid-translocating ATPase compare
mRNA_3121 11489 +1.3 0.7 KOG1039 Predicted E3 ubiquitin ligase compare
mRNA_5386 13754 +1.3 0.1 Hypothetical Protein compare
mRNA_7554 15922 +1.3 0.2 K07359 CAMKK calcium/calmodulin-dependent protein kinase kinase compare
mRNA_7424 15792 +1.3 0.8 Hypothetical Protein compare
mRNA_1213 9581 +1.3 0.7 KOG1205 Predicted dehydrogenase compare
mRNA_6141 14509 +1.2 1.9 HMMPfam-GGL domain-PF00631,SUPERFAMILY--SSF48670 compare
mRNA_547 8915 +1.2 1.7 KOG2385 Uncharacterized conserved protein compare
mRNA_7169 15537 +1.2 0.9 K13137 STRAP, UNRIP serine-threonine kinase receptor-associated protein compare
mRNA_273 8641 +1.2 3.2 K15174 PAF1 RNA polymerase II-associated factor 1 compare
mRNA_8216 16584 +1.2 1.4 K14376 PAP poly(A) polymerase compare
mRNA_3917 12285 +1.2 2.2 KOG4479 Transcription factor e(y)2 compare
mRNA_6799 15167 +1.2 0.2 K00033 PGD, gnd, gntZ 6-phosphogluconate dehydrogenase compare
mRNA_8199 16567 +1.2 0.8 Hypothetical Protein compare
mRNA_7869 16237 +1.2 1.9 KOG4366 Predicted thioesterase compare
mRNA_2798 11166 +1.2 1.7 K03537 POP5 ribonuclease P/MRP protein subunit POP5 compare
mRNA_2189 10557 +1.2 3.7 K11236 CDC24 cell division control protein 24 compare
mRNA_7510 15878 +1.2 6.0 K11644 SIN3A paired amphipathic helix protein Sin3a compare
mRNA_1710 10078 +1.2 2.4 Hypothetical Protein compare
mRNA_1912 10280 +1.2 9.5 K04450 ATF2, CREBP1 cyclic AMP-dependent transcription factor ATF-2 compare
mRNA_7417 15785 +1.2 1.2 K03353 APC6, CDC16 anaphase-promoting complex subunit 6 compare
mRNA_8148 16516 +1.2 1.5 HMMPfam-START domain-PF01852,ProSiteProfiles-START domain profile.-PS50848,SUPERFAMILY--SSF55961 compare
mRNA_753 9121 +1.2 3.7 K02737 PSMB5 20S proteasome subunit beta 5 compare
mRNA_7572 15940 +1.2 0.9 Hypothetical Protein compare
mRNA_5548 13916 +1.2 2.1 KOG4006 Anti-proliferation factor BTG1/TOB compare
mRNA_2375 10743 +1.2 3.7 Hypothetical Protein compare
mRNA_1480 9848 +1.1 0.3 KOG0254 Predicted transporter (major facilitator superfamily) compare
mRNA_7116 15484 +1.1 4.7 K04393 CDC42 cell division control protein 42 compare
mRNA_1083 9451 +1.1 0.8 Hypothetical Protein compare
mRNA_109 8477 +1.1 0.7 Hypothetical Protein compare
mRNA_6154 14522 +1.1 12.8 K16667 PTPRG receptor-type tyrosine-protein phosphatase gamma compare
mRNA_2677 11045 +1.1 3.0 ProSitePatterns-Zinc finger C2H2 type domain signature.-PS00028,ProSiteProfiles-Zinc finger C2H2 type domain profile.-PS50157 compare
mRNA_2405 10773 +1.1 13.0 KOG1910 Uncharacterized conserved protein compare
mRNA_2822 11190 +1.1 0.4 SUPERFAMILY--SSF52047 compare
mRNA_4730 13098 +1.1 2.3 K06062 PCAF, KAT2, GCN5 histone acetyltransferase compare
mRNA_3286 11654 +1.1 0.4 Hypothetical Protein compare
mRNA_4317 12685 +1.1 2.5 K07025 K07025 putative hydrolase of the HAD superfamily compare
mRNA_65 8433 +1.1 2.0 K12882 NCBP1, CBP80 nuclear cap-binding protein subunit 1 compare
mRNA_1806 10174 +1.1 1.7 BLAST related to C2H2 zinc finger protein [Ustilago hordei] compare
mRNA_6224 14592 +1.1 1.7 Hypothetical Protein compare
mRNA_8067 16435 +1.0 2.7 K12399 AP3S AP-3 complex subunit sigma compare
mRNA_5460 13828 +1.0 2.0 Hypothetical Protein compare
mRNA_7378 15746 +1.0 1.6 KOG1180 Acyl-CoA synthetase compare
mRNA_1243 9611 +1.0 2.2 K02493 hemK, prmC, HEMK release factor glutamine methyltransferase compare
mRNA_3015 11383 +1.0 1.0 KOG3252 Uncharacterized conserved protein compare
mRNA_5624 13992 +1.0 0.9 KOG1611 Predicted short chain-type dehydrogenase compare
mRNA_6951 15319 +1.0 2.1 ProSiteProfiles-Ribonuclease III family domain profile.-PS50142,SUPERFAMILY--SSF69065 compare
mRNA_1741 10109 +1.0 2.3 HMMPfam-Calcipressin-PF04847 compare
mRNA_5174 13542 +1.0 2.6 Hypothetical Protein compare
mRNA_1556 9924 +1.0 2.2 KOG3114 Uncharacterized conserved protein compare
mRNA_8246 16614 +1.0 0.5 Hypothetical Protein compare
mRNA_3302 11670 +1.0 3.0 K07232 chaC cation transport protein ChaC compare
mRNA_8365 16733 +1.0 2.7 Hypothetical Protein compare
mRNA_3729 12097 +1.0 3.5 K15280 SLC35C2 solute carrier family 35, member C2 compare
mRNA_8013 16381 +1.0 3.2 SUPERFAMILY--SSF58113 compare
mRNA_8370 16738 +1.0 2.6 K12525 metL bifunctional aspartokinase / homoserine dehydrogenase 2 compare
mRNA_3890 12258 +1.0 4.5 HMMPfam-Pal1 cell morphology protein-PF08316 compare
mRNA_263 8631 +1.0 5.4 K01537 E3.6.3.8 Ca2+-transporting ATPase compare
mRNA_5808 14176 +1.0 1.1 HMMPfam-Cytochrome oxidase complex assembly protein 1-PF08695 compare
mRNA_6819 15187 +1.0 4.2 SUPERFAMILY--SSF103107 compare
mRNA_275 8643 +1.0 0.8 BLAST nitrogen assimilation transcription factor [Rhodo... compare
mRNA_876 9244 +1.0 2.9 K00297 metF, MTHFR methylenetetrahydrofolate reductase (NADPH) compare
mRNA_2784 11152 +1.0 6.6 K20241 WDR44, RAB11BP WD repeat-containing protein 44 compare
mRNA_1982 10350 +1.0 2.9 HMMPfam-Copper binding proteins, plastocyanin/azurin family-PF00127,ProSiteProfiles-Prokaryotic membrane lipoprotein lipid attachment site profile.-PS51257,SUPERFAMILY--SSF49503 compare
mRNA_4605 12973 +1.0 1.9 KOG0254 Predicted transporter (major facilitator superfamily) compare
mRNA_3834 12202 +0.9 1.6 Hypothetical Protein compare
mRNA_7044 15412 +0.9 3.9 KOG4299 PHD Zn-finger protein compare
mRNA_1188 9556 +0.9 0.6 Hypothetical Protein compare
mRNA_6839 15207 +0.9 5.2 K17257 ITFG1 integrin alpha FG-GAP repeat containing protein 1 compare
mRNA_7900 16268 +0.9 2.3 Hypothetical Protein compare
mRNA_7078 15446 +0.9 1.1 Hypothetical Protein compare
mRNA_967 9335 +0.9 1.0 HMMPfam-Starch binding domain-PF00686,SUPERFAMILY--SSF49452 compare
mRNA_7019 15387 +0.9 2.5 K13212 LUC7L2 RNA-binding protein Luc7-like 2 compare
mRNA_6221 14589 +0.9 2.6 HMMPfam-BTB/POZ domain-PF00651,ProSiteProfiles-BTB domain profile.-PS50097,SMART-Broad-Complex, Tramtrack and Bric a brac-SM00225,SUPERFAMILY--SSF54695 compare
mRNA_6489 14857 +0.9 6.8 KOG0327 Translation initiation factor 4F, helicase subunit (eIF-4A) and related helicases compare
mRNA_7146 15514 +0.9 2.7 Hypothetical Protein compare
mRNA_3498 11866 +0.9 1.6 K18064 ACR2 arsenical-resistance protein 2 compare
mRNA_3781 12149 +0.9 3.1 K12821 PRPF40, PRP40 pre-mRNA-processing factor 40 compare
mRNA_5846 14214 +0.9 2.2 K04508 TBL1 transducin (beta)-like 1 compare
mRNA_5102 13470 +0.9 7.4 KOG0619 FOG Leucine rich repeat compare
mRNA_8138 16506 +0.9 2.5 Hypothetical Protein compare
mRNA_3687 12055 +0.9 1.3 K14837 NOP12 nucleolar protein 12 compare
mRNA_4509 12877 +0.9 1.8 HMMPfam-Ctr copper transporter family-PF04145 compare
mRNA_5589 13957 +0.9 1.7 HMMPfam-Region in Clathrin and VPS-PF00637,ProSiteProfiles-Clathrin heavy-chain (CHCR) repeat profile.-PS50236,SMART-Clathrin heavy chain repeat homology-SM00299,SUPERFAMILY--SSF48371 compare
mRNA_8205 16573 +0.9 1.5 K11339 MORF4L1, MRG15, EAF3 mortality factor 4-like protein 1 compare
mRNA_6975 15343 +0.9 5.5 Hypothetical Protein compare
mRNA_8159 16527 +0.9 2.5 K17607 TIPRL, TIP41 type 2A phosphatase activator TIP41 compare
mRNA_7449 15817 +0.9 1.9 BLAST GH19984 [Drosophila grimshawi] compare
mRNA_4968 13336 +0.9 4.5 KOG4464 Signaling protein RIC-8/synembryn (regulates neurotransmitter secretion) compare
mRNA_6239 14607 +0.9 1.5 K01372 BLMH, pepC bleomycin hydrolase compare
mRNA_3410 11778 +0.9 1.9 BLAST allergen [Malassezia sympodialis ATCC 42132] compare
mRNA_8245 16613 +0.9 1.6 HMMPfam-Mitochondrial carrier protein-PF00153,ProSiteProfiles-Solute carrier (Solcar) repeat profile.-PS50920,SUPERFAMILY--SSF103506 compare
mRNA_3254 11622 +0.9 0.6 K12161 URM1 ubiquitin related modifier 1 compare
mRNA_4049 12417 +0.9 2.0 HMMPfam-Rare lipoprotein A (RlpA)-like double-psi beta-barrel-PF03330,SUPERFAMILY--SSF50685 compare
mRNA_6195 14563 +0.9 1.7 SUPERFAMILY--SSF52047 compare
mRNA_4777 13145 +0.8 -0.0 Hypothetical Protein compare
mRNA_5581 13949 +0.8 2.6 KOG1198 Zinc-binding oxidoreductase compare
mRNA_5603 13971 +0.8 3.2 K09523 DNAJC3 DnaJ homolog subfamily C member 3 compare
mRNA_7551 15919 +0.8 4.4 KOG1032 Uncharacterized conserved protein, contains GRAM domain compare
mRNA_192 8560 +0.8 2.2 HMMPfam-SUR7/PalI family-PF06687 compare
mRNA_1394 9762 +0.8 1.3 K04907 KCNH4 potassium voltage-gated channel Eag-related subfamily H member 4 compare
mRNA_7486 15854 +0.8 2.0 K08287 E2.7.12.1 dual-specificity kinase compare
mRNA_4723 13091 +0.8 0.8 Hypothetical Protein compare
mRNA_4992 13360 +0.8 2.9 Hypothetical Protein compare
mRNA_4961 13329 +0.8 0.5 Hypothetical Protein compare
mRNA_5204 13572 +0.8 0.7 Hypothetical Protein compare
mRNA_331 8699 +0.8 1.5 K03940 NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7 compare
mRNA_1260 9628 +0.8 7.9 Hypothetical Protein compare
mRNA_6305 14673 +0.8 1.0 HMMPfam-FAM72 protein-PF14976,ProSitePatterns-Zinc finger C2H2 type domain signature.-PS00028 compare
mRNA_1934 10302 +0.8 4.9 HMMPfam-Cryptococcal mannosyltransferase 1-PF11735 compare
mRNA_6823 15191 +0.8 0.8 BLAST TNFR/NGFR cysteine-rich region family protein [Rh... compare
mRNA_6674 15042 +0.8 2.5 HMMPfam-MYND finger-PF01753,ProSitePatterns-Zinc finger MYND-type signature.-PS01360,ProSiteProfiles-Zinc finger MYND-type profile.-PS50865,SUPERFAMILY--SSF144232 compare
mRNA_7343 15711 +0.8 1.8 K04798 pfdB, PFDN6 prefoldin beta subunit compare
mRNA_817 9185 +0.8 2.4 K02208 CDK8_11 cyclin-dependent kinase 8/11 compare
mRNA_2081 10449 +0.8 4.8 BLAST 163.m06341p [Cryptococcus neoformans] compare
mRNA_4618 12986 +0.8 0.9 Hypothetical Protein compare
mRNA_2660 11028 +0.8 2.2 Hypothetical Protein compare
mRNA_8117 16485 +0.8 3.7 K06041 kdsD, kpsF arabinose-5-phosphate isomerase compare
mRNA_6553 14921 +0.8 4.1 SUPERFAMILY--SSF52266 compare
mRNA_1916 10284 +0.8 1.7 HMMPfam-bZIP transcription factor-PF00170,HMMPfam-Domain of unknown function (DUF3425)-PF11905,ProSitePatterns-Basic-leucine zipper (bZIP) domain signature.-PS00036,SMART-basic region leucin zipper-SM00338,SUPERFAMILY--SSF57959 compare
mRNA_2741 11109 +0.8 1.1 HMMPfam-Telomeric single stranded DNA binding POT1/CDC13-PF02765,SUPERFAMILY--SSF50249 compare
mRNA_6536 14904 +0.8 3.0 HMMPfam-Protein of unknown function (DUF837)-PF05769 compare
mRNA_3107 11475 +0.8 2.7 K11412 SIRT2, SIR2L2 NAD-dependent deacetylase sirtuin 2 compare
mRNA_6346 14714 +0.8 3.5 HMMPfam-Protein of unknown function (DUF938)-PF06080,SUPERFAMILY--SSF53335 compare
mRNA_6304 14672 +0.8 3.2 Hypothetical Protein compare
mRNA_2487 10855 +0.8 1.7 BLAST putative protein [Melanopsichium pennsylvanicum 4] compare
mRNA_3626 11994 +0.8 1.8 BLAST SH3 domain-containing protein [Rhizoctonia solani AG-... compare
mRNA_5934 14302 +0.8 2.1 HMMPfam-Mitochondrial carrier protein-PF00153,ProSiteProfiles-Solute carrier (Solcar) repeat profile.-PS50920,SUPERFAMILY--SSF103506 compare
mRNA_7515 15883 +0.8 7.7 K07827 KRAS, KRAS2 GTPase KRas compare
mRNA_4917 13285 +0.8 0.8 KOG2920 Predicted methyltransferase compare
mRNA_1677 10045 +0.8 5.3 K15620 GOLPH3, GPP34 golgi phosphoprotein 3 compare
mRNA_4637 13005 +0.8 2.9 Hypothetical Protein compare
mRNA_6322 14690 +0.8 3.9 K09420 MYB myb proto-oncogene protein compare
mRNA_1215 9583 +0.8 0.8 Hypothetical Protein compare
mRNA_5723 14091 +0.8 1.5 K15447 TRM44, METTL19 tRNASer (uridine44-2'-O)-methyltransferase compare
mRNA_7450 15818 +0.8 0.8 BLAST proteophosphoglycan protein, putative [Rhizoctonia so... compare
mRNA_2368 10736 +0.8 1.7 Hypothetical Protein compare
mRNA_1876 10244 +0.8 1.1 Hypothetical Protein compare
mRNA_70 8438 +0.8 2.0 HMMPfam-Membrane-associating domain-PF01284 compare
mRNA_2995 11363 +0.8 4.8 K20290 COG3, SEC34 conserved oligomeric Golgi complex subunit 3 compare
mRNA_5747 14115 +0.8 3.3 HMMPfam-F-box-like-PF12937 compare
mRNA_6582 14950 +0.8 1.5 K11517 HAO (S)-2-hydroxy-acid oxidase compare
mRNA_2589 10957 +0.8 2.2 Hypothetical Protein compare
mRNA_7422 15790 +0.8 1.8 Hypothetical Protein compare
mRNA_2688 11056 +0.8 1.3 Hypothetical Protein compare
mRNA_6529 14897 +0.8 3.6 K03626 EGD2, NACA nascent polypeptide-associated complex subunit alpha compare
mRNA_1866 10234 +0.8 2.2 KOG4455 Uncharacterized conserved protein compare
mRNA_5151 13519 +0.7 2.7 HMMPfam-SUR7/PalI family-PF06687 compare
mRNA_6710 15078 +0.7 2.7 SUPERFAMILY--SSF50685 compare
mRNA_6301 14669 +0.7 1.8 Hypothetical Protein compare
mRNA_6539 14907 +0.7 4.3 K19800 SCH9 serine/threonine protein kinase SCH9 compare
mRNA_3012 11380 +0.7 2.7 K06269 PPP1C serine/threonine-protein phosphatase PP1 catalytic subunit compare
mRNA_4662 13030 +0.7 1.7 K20352 TMED10, ERV25 p24 family protein delta-1 compare
mRNA_4802 13170 +0.7 3.6 K09313 CUTL homeobox protein cut-like compare
mRNA_8394 16762 +0.7 3.9 KOG3680 Uncharacterized conserved protein compare
mRNA_6562 14930 +0.7 2.0 K20353 SEC16 COPII coat assembly protein SEC16 compare


Specific Phenotypes

None in this experiment

For Rhodosporidium toruloides IFO0880 in auxotrophy experiments

For auxotrophy unknown across organisms