MetaCyc Pathway: superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass in Rhodosporidium toruloides IFO0880

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Glucose-6-phosphate isomerase:
D-glucopyranose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
mRNA_1221 (9589)
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
mRNA_491 (8859)
mRNA_499 (8867)
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
mRNA_7052 (15420)
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
mRNA_7055 (15423)
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
mRNA_2245 (10613)
mRNA_3311 (11679)
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
mRNA_6808 (15176)
mRNA_7700 (16068)
mRNA_8276 (16644)
mRNA_932 (9300)
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
mRNA_7353 (15721)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
mRNA_4025 (12393)
mRNA_1542 (9910)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
No genes
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
mRNA_4451 (12819)
mRNA_8034 (16402)
mRNA_669 (9037)
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
mRNA_2701 (11069)
mRNA_4634 (13002)
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)
No genes
pyruvate + coenzyme A + NAD+→acetyl-CoA + CO2 + NADH (EC 1.2.1.104)
mRNA_5262 (13630)
mRNA_5354 (13722)
mRNA_5580 (13948)
mRNA_5758 (14126)
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16)
mRNA_2960 (11328)
mRNA_2963 (11331)
mRNA_180 (8548)
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
mRNA_3256 (11624)
mRNA_6232 (14600)
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
mRNA_3256 (11624)
mRNA_6232 (14600)
Isocitrate lyase:
D-threo-isocitrate→glyoxylate + succinate (EC 4.1.3.1)
mRNA_5654 (14022)
mRNA_5794 (14162)
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→2-oxoglutarate + CO2 + NADPH (EC 1.1.1.42)
mRNA_2761 (11129)
2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
mRNA_5262 (13630)
mRNA_5580 (13948)
Malate synthase:
acetyl-CoA + glyoxylate + H2O→(S)-malate + coenzyme A + H+ (EC 2.3.3.9)
mRNA_1089 (9457)
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
mRNA_7599 (15967)
mRNA_7776 (16144)
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1)
mRNA_3261 (11629)
mRNA_3609 (11977)
mRNA_7913 (16281)
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate (EC 4.2.1.2)
mRNA_5633 (14001)
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)
mRNA_2246 (10614)
mRNA_2810 (11178)
mRNA_4393 (12761)
mRNA_5549 (13917)
(S)-malate[in] + an electron-transfer quinone→oxaloacetate[in] + an electron-transfer quinol (EC 1.1.5.4)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information