MetaCyc Pathway: heme b biosynthesis I (aerobic) in Rhodosporidium toruloides IFO0880

Uroporphyrinogen decarboxylase: uroporphyrinogen-III + 4 H+→coproporphyrinogen III + 4 CO2 (EC 4.1.1.37)

mRNA_5811 (14179)

Coproporphyrinogen oxidase: coproporphyrinogen III + dioxygen + 2 H+→protoporphyrinogen IX + 2 CO2 + 2 H2O (EC 1.3.3.3)

mRNA_5829 (14197)

Protoporphyrinogen oxidase: protoporphyrinogen IX + 3 dioxygen→protoporphyrin IX + 3 hydrogen peroxide (EC 1.3.3.4)

mRNA_3499 (11867)

Ferrochelatase (in reverse): protoporphyrin IX + Fe2+→protoheme + 2 H+ (EC 4.99.1.1)

mRNA_7907 (16275)

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information