MetaCyc Pathway: L-lysine degradation XI (mammalian) in Rhodosporidium toruloides IFO0880

Add experiment(s):


Saccharopine dehydrogenase (NADP(+), L-lysine-forming) (in reverse):
L-lysine + 2-oxoglutarate + NADPH + H+→L-saccharopine + NADP+ + H2O
(EC 1.5.1.8)
mRNA_2209 (10577)
Saccharopine dehydrogenase (NAD(+), L-glutamate-forming):
L-saccharopine + NAD+ + H2O→(S)-2-amino-6-oxohexanoate + L-glutamate + NADH + H+
(EC 1.5.1.9)
mRNA_2209 (10577)
L-aminoadipate-semialdehyde dehydrogenase:
(S)-2-amino-6-oxohexanoate + NAD(P)+ + H2O→L-2-aminoadipate + NAD(P)H + 2 H+
(EC 1.2.1.31)
mRNA_7446 (15814)
mRNA_1127 (9495)
2-aminoadipate transaminase:
L-2-aminoadipate + 2-oxoglutarate→2-oxoadipate + L-glutamate
(EC 2.6.1.39)
No genes
2-oxoadipate + coenzyme A + NAD+→glutaryl-CoA + CO2 + NADH (EC 1.2.1.105)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information