MetaCyc Pathway: ectoine biosynthesis in Rhodosporidium toruloides IFO0880

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Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP
(EC 2.7.2.4)
mRNA_6294 (14662)
mRNA_8370 (16738)
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate
(EC 1.2.1.11)
mRNA_1962 (10330)
Diaminobutyrate--2-oxoglutarate transaminase (in reverse):
L-aspartate 4-semialdehyde + L-glutamate→L-2,4-diaminobutanoate + 2-oxoglutarate
(EC 2.6.1.76)
No genes
Diaminobutyrate acetyltransferase:
L-2,4-diaminobutanoate + acetyl-CoA→(2S)-4-acetamido-2-aminobutanoate + coenzyme A + H+
(EC 2.3.1.178)
No genes
Ectoine synthase:
(2S)-4-acetamido-2-aminobutanoate→ectoine + H2O
(EC 4.2.1.108)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information