MetaCyc Pathway: formaldehyde assimilation I (serine pathway) in Rhodosporidium toruloides IFO0880

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formaldehyde + a tetrahydrofolate→a 5,10-methylenetetrahydrofolate + H2O (spontaneous)
No genes
Glycine hydroxymethyltransferase (in reverse):
a 5,10-methylenetetrahydrofolate + glycine + H2O→L-serine + a tetrahydrofolate (EC 2.1.2.1)
mRNA_3893 (12261)
mRNA_4293 (12661)
mRNA_4944 (13312)
mRNA_1299 (9667)
Serine--glyoxylate transaminase:
L-serine + glyoxylate→glycine + hydroxypyruvate (EC 2.6.1.45)
mRNA_451 (8819)
Hydroxypyruvate reductase (in reverse):
hydroxypyruvate + NAD(P)H + H+→D-glycerate + NAD(P)+ (EC 1.1.1.81)
No genes
D-glycerate + ATP→2-phospho-D-glycerate + ADP + H+ (EC 2.7.1.165)
No genes
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
mRNA_4451 (12819)
mRNA_8034 (16402)
mRNA_669 (9037)
2-phospho-D-glycerate→3-phospho-D-glycerate (EC 5.4.2.11)
No genes
Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogencarbonate→oxaloacetate + phosphate (EC 4.1.1.31)
No genes
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
mRNA_2246 (10614)
mRNA_2810 (11178)
mRNA_4393 (12761)
mRNA_5549 (13917)
Malate--CoA ligase:
(S)-malate + ATP + coenzyme A→(S)-malyl-CoA + ADP + phosphate (EC 6.2.1.9)
No genes
Malyl-CoA lyase:
(S)-malyl-CoA→glyoxylate + acetyl-CoA (EC 4.1.3.24)
No genes
2 acetyl-CoA + CO2 + an oxidized electron-transfer flavoprotein + 2 NADPH + 2 H+→glyoxylate + coenzyme A + a reduced electron-transfer flavoprotein + 2 NADP+ + propanoyl-CoA
No genes
Serine--glyoxylate transaminase (in reverse):
glyoxylate + L-serine→glycine + hydroxypyruvate (EC 2.6.1.45)
mRNA_451 (8819)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information