MetaCyc Pathway: L-isoleucine biosynthesis V in Rhodosporidium toruloides IFO0880

Add experiment(s):


Acetate--CoA ligase:
2-methylbutanoate + ATP + coenzyme A→(2S)-2-methylbutanoyl-CoA + AMP + diphosphate
(EC 6.2.1.1)
mRNA_6223 (14591)
mRNA_6229 (14597)
mRNA_7532 (15900)
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) (in reverse):
(2S)-2-methylbutanoyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→(3S)-3-methyl-2-oxopentanoate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster
(EC 1.2.7.7)
No genes
Branched-chain-amino-acid transaminase (in reverse):
(3S)-3-methyl-2-oxopentanoate + L-glutamate→L-isoleucine + 2-oxoglutarate
(EC 2.6.1.42)
mRNA_5646 (14014)
mRNA_6242 (14610)
mRNA_6485 (14853)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information