MetaCyc Pathway: methanofuran biosynthesis in Rhodosporidium toruloides IFO0880

Add experiment(s):


2 D-glyceraldehyde 3-phosphate→(5-formylfuran-3-yl)methyl phosphate + phosphate + 2 H2O (EC 4.2.3.153)
No genes
Tyrosine decarboxylase:
L-tyrosine + H+→tyramine + CO2
(EC 4.1.1.25; 4.1.1.28)
mRNA_1736 (10104)
mRNA_5309 (13677)
tyramine + L-glutamate + ATP→γ-glutamyltyramine + ADP + H+ + phosphate (EC 6.3.4.24)
No genes
(5-formylfuran-3-yl)methyl phosphate + L-alanine→[5-(aminomethyl)furan-3-yl]methyl phosphate + pyruvate (EC 2.6.1.108)
No genes
[5-(aminomethyl)furan-3-yl]methyl phosphate + ATP→[5-(aminomethyl)furan-3-yl]methyl diphosphate + ADP (EC 2.7.4.31)
No genes
γ-glutamyltyramine + [5-(aminomethyl)furan-3-yl]methyl diphosphate→(4-{4-[2-(γ-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + diphosphate (EC 2.5.1.131)
No genes
(4-{4-[2-(γ-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + 2 L-glutamate→methanofuran b + 2 H2O
No genes
(4-{4-[2-(γ-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + 6 L-glutamate→methanofuran d + 6 H2O
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information