MetaCyc Pathway: L-threonine degradation I in Rhodosporidium toruloides IFO0880
Threonine ammonia-lyase: L-threonine→(2Z)-2-aminobut-2-enoate + H+ + H2O (EC 4.3.1.19) |
mRNA |
mRNA |
1-aminocyclopropane-1-carboxylate deaminase: (2Z)-2-aminobut-2-enoate→2-iminobutanoate (spontaneous) (EC 3.5.99.7; 4.3.1.19; 4.4.1.1; 4.4.1.11; 4.4.1.2) |
mRNA |
mRNA |
mRNA |
2-iminobutanoate + H+ + H2O→2-oxobutanoate + ammonium (spontaneous) (EC 3.5.99.10; 3.5.99.7; 4.3.1.19; 4.4.1.1; 4.4.1.11; 4.4.1.2) |
mRNA |
mRNA |
mRNA |
mRNA |
2-oxobutanoate + coenzyme A→propanoyl-CoA + formate |
No genes |
propanoyl-CoA + phosphate→propanoyl phosphate + coenzyme A (EC 2.3.1.222) |
No genes |
Acetate kinase (in reverse): propanoyl phosphate + ADP→propanoate + ATP (EC 2.7.2.1; 2.7.2.14; 2.7.2.15; 2.7.2.7) |
mRNA |
Links:
- Pathway details at MetaCyc
- Fitness data for 5 genes
- All MetaCyc pathways for Rhodosporidium toruloides IFO0880
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information