MetaCyc Pathway: superpathway of bacteriochlorophyll a biosynthesis in Rhodosporidium toruloides IFO0880

Add experiment(s):


5-aminolevulinate synthase:
glycine + H+ + succinyl-CoA→5-aminolevulinate + CO2 + coenzyme A (EC 2.3.1.37)
mRNA_309 (8677)
Porphobilinogen synthase:
2 5-aminolevulinate→porphobilinogen + H+ + 2 H2O (EC 4.2.1.24)
mRNA_5026 (13394)
Hydroxymethylbilane synthase:
4 porphobilinogen + H2O→preuroporphyrinogen + 4 ammonium (EC 2.5.1.61)
mRNA_6350 (14718)
Uroporphyrinogen-III synthase:
preuroporphyrinogen→uroporphyrinogen-III + H2O (EC 4.2.1.75)
No genes
Uroporphyrinogen decarboxylase:
uroporphyrinogen-III + 4 H+→coproporphyrinogen III + 4 CO2 (EC 4.1.1.37)
mRNA_5811 (14179)
coproporphyrinogen III + 2 S-adenosyl-L-methionine→protoporphyrinogen IX + 2 CO2 + 2 5'-deoxyadenosine + 2 L-methionine (EC 1.3.98.3)
No genes
protoporphyrinogen IX[in] + 3 a menaquinone→protoporphyrin IX[in] + 3 a menaquinol (EC 1.3.5.3)
No genes
Magnesium chelatase:
protoporphyrin IX + ATP + Mg2+ + H2O→Mg-protoporphyrin + ADP + 3 H+ + phosphate (EC 6.6.1.1)
No genes
Magnesium protoporphyrin IX methyltransferase:
Mg-protoporphyrin + S-adenosyl-L-methionine→magnesium-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine (EC 2.1.1.11)
No genes
magnesium-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-methionine + H2O→131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-deoxyadenosine + L-methionine + H+ (EC 1.21.98.3)
No genes
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-methionine→131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-deoxyadenosine + L-methionine + H+ (EC 1.21.98.3)
No genes
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-methionine→3,8-divinyl protochlorophyllide a + 5'-deoxyadenosine + L-methionine + 2 H+ (EC 1.21.98.3)
No genes
3,8-divinyl protochlorophyllide a + 2 ATP + 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H2O→chlorophyllide a2 + 2 ADP + 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 phosphate (EC 1.3.7.7)
No genes
chlorophyllide a2 + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→chlorophyllide a + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.3.7.13)
No genes
Divinyl chlorophyllide a 8-vinyl-reductase (in reverse):
chlorophyllide a2 + NADPH + H+→chlorophyllide a + NADP+ (EC 1.3.1.75)
No genes
chlorophyllide a + H2O→3-devinyl-3-(1-hydroxyethyl)chlorophyllide a (EC 4.2.1.165)
No genes
chlorophyllide a + ATP + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster + H2O→3-deacetyl-3-vinylbacteriochlorophyllide a + ADP + 2 an oxidized ferredoxin [iron-sulfur] cluster + phosphate (EC 1.3.7.15)
No genes
3-devinyl-3-(1-hydroxyethyl)chlorophyllide a + NAD+→3-acetyl-3-devinylchlorophyllide a + NADH + H+ (EC 1.1.1.396)
No genes
3-devinyl-3-(1-hydroxyethyl)chlorophyllide a + ATP + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster + H2O→3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a + ADP + 2 an oxidized ferredoxin [iron-sulfur] cluster + phosphate (EC 1.3.7.15)
No genes
3-deacetyl-3-vinylbacteriochlorophyllide a + H2O→3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a (EC 4.2.1.165)
No genes
3-acetyl-3-devinylchlorophyllide a + ATP + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster + H2O→bacteriochlorophyllide a + ADP + 2 an oxidized ferredoxin [iron-sulfur] cluster + phosphate (EC 1.3.7.15)
No genes
3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a + NAD+→bacteriochlorophyllide a + NADH + H+ (EC 1.1.1.396)
No genes
bacteriochlorophyllide a + geranylgeranyl diphosphate + H+→geranylgeranyl bacteriochlorophyllide a + diphosphate (EC 2.5.1.133)
No genes
geranylgeranyl bacteriochlorophyllide a + NADPH + H+→phyta-2,10,14-trienyl bacteriochlorophyllide a + NADP+ (EC 1.3.1.111)
No genes
phyta-2,10,14-trienyl bacteriochlorophyllide a + NADPH + H+→phyta-2,14-dienyl bacteriochlorophyllide a + NADP+ (EC 1.3.1.111)
No genes
phyta-2,14-dienyl bacteriochlorophyllide a + NADPH + H+→bacteriochlorophyll a + NADP+ (EC 1.3.1.111)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information