MetaCyc Pathway: superpathway of glyoxylate cycle and fatty acid degradation in Rhodosporidium toruloides IFO0880

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a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
Acyl-CoA oxidase:
a 2,3,4-saturated fatty acyl CoA + dioxygen→a (2E)-2-enoyl-CoA + hydrogen peroxide
(EC 1.3.3.6)
mRNA_4374 (12742)
mRNA_1332 (9700)
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
mRNA_2742 (11110)
mRNA_3539 (11907)
mRNA_6437 (14805)
mRNA_8147 (16515)
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
mRNA_2835 (11203)
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA
(EC 2.3.1.16)
mRNA_5445 (13813)
mRNA_5687 (14055)
mRNA_6860 (15228)
mRNA_310 (8678)
mRNA_517 (8885)
mRNA_697 (9065)
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+
(EC 2.3.3.1; 2.3.3.16)
mRNA_2960 (11328)
mRNA_2963 (11331)
mRNA_180 (8548)
Aconitate hydratase:
citrate→cis-aconitate + H2O
(EC 4.2.1.3)
mRNA_3256 (11624)
mRNA_6232 (14600)
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate
(EC 4.2.1.3)
mRNA_3256 (11624)
mRNA_6232 (14600)
Isocitrate lyase:
D-threo-isocitrate→glyoxylate + succinate
(EC 4.1.3.1)
mRNA_5654 (14022)
mRNA_5794 (14162)
Malate synthase:
acetyl-CoA + glyoxylate + H2O→(S)-malate + coenzyme A + H+
(EC 2.3.3.9)
mRNA_1089 (9457)
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol
(EC 1.3.5.1)
mRNA_3261 (11629)
mRNA_3609 (11977)
mRNA_7913 (16281)
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate
(EC 4.2.1.2)
mRNA_5633 (14001)
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+
(EC 1.1.1.37; 1.1.1.38)
mRNA_2246 (10614)
mRNA_2810 (11178)
mRNA_4393 (12761)
mRNA_5549 (13917)
Phosphoenolpyruvate carboxykinase (ATP):
oxaloacetate + ATP→phosphoenolpyruvate + ADP + CO2
(EC 4.1.1.49)
mRNA_2473 (10841)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information