MetaCyc Pathway: ubiquinol-10 biosynthesis (late decarboxylation) in Rhodosporidium toruloides IFO0880

Add experiment(s):


(2E,6E)-farnesyl diphosphate + 7 3-methylbut-3-en-1-yl diphosphate→all-trans-decaprenyl diphosphate + 7 diphosphate (EC 2.5.1.91)
No genes
4-hydroxybenzoate nonaprenyltransferase:
all-trans-decaprenyl diphosphate + 4-hydroxybenzoate→4-hydroxy-3-decaprenylbenzoate + diphosphate
(EC 2.5.1.39)
mRNA_6869 (15237)
4-hydroxy-3-decaprenylbenzoate + NADPH + dioxygen + H+→3,4-dihydroxy-5-all-trans-decaprenylbenzoate + NADP+ + H2O (EC 1.14.13.M81)
No genes
Hexaprenyldihydroxybenzoate methyltransferase:
3,4-dihydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-methionine→3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-homocysteine + H+
(EC 2.1.1.114)
No genes
3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H+→6-(all-trans-decaprenyl)-2-methoxy-phenol + CO2
No genes
6-(all-trans-decaprenyl)-2-methoxy-phenol + NADPH + dioxygen + H+all trans-decaprenyl-2-methoxy-6-1,4-benzoquinol + NADP+ + H2O (EC 1.14.13.M56)
No genes
all trans-decaprenyl-2-methoxy-6-1,4-benzoquinol + S-adenosyl-L-methionine→6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.201)
No genes
6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol + a reduced unknown two electron carrier + dioxygen→3-demethylubiquinol-10 + an oxidized unknown electron carrier + H2O (EC 1.14.99.60)
No genes
3-demethylubiquinone-9 3-O-methyltransferase:
3-demethylubiquinol-10 + S-adenosyl-L-methionine→ubiquinol-10 + S-adenosyl-L-homocysteine + H+
(EC 2.1.1.64)
mRNA_3097 (11465)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information