Isochorismate synthase:
chorismate→isochorismate (EC 5.4.4.2) |
| No genes |
| glycine + ATP→(glycyl)adenylate + diphosphate (EC 6.2.1.66) |
| No genes |
| L-threonine + ATP + H+→(L-threonyl)adenylate + diphosphate (EC 6.2.1.70) |
| No genes |
Isochorismatase:
isochorismate + H2O→(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate (EC 3.3.2.1) |
| mRNA_4258 (12626) |
| (L-threonyl)adenylate + a [DhbF non-ribosomal peptide synthase]→an L-threonyl-[DhbF non-ribosomal peptide synthase] + AMP + H+ (EC 6.2.1.70) |
| No genes |
| (glycyl)adenylate + a [DhbF non-ribosomal peptide synthase]→a glycyl-[DhbF non-ribosomal peptide synthase] + AMP (EC 6.2.1.66) |
| No genes |
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase:
(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD+→2,3-dihydroxybenzoate + NADH + H+ (EC 1.3.1.28) |
| No genes |
| 2,3-dihydroxybenzoate + ATP + H+→(2,3-dihydroxybenzoyl)adenylate + diphosphate (EC 6.2.1.71) |
| No genes |
| (2,3-dihydroxybenzoyl)adenylate + a holo-[DhbB aryl-carrier protein]→a 2,3-dihydroxybenzoyl-[DhbB aryl-carrier protein] + AMP + H+ (EC 6.2.1.71) |
| No genes |
| a 2,3-dihydroxybenzoyl-[DhbB aryl-carrier protein] + a glycyl-[DhbF non-ribosomal peptide synthase]→a 2,3-dihydroxybenzoyl-glycyl-[DhbF non-ribosomal peptide synthase] + a holo-[DhbB aryl-carrier protein] + H+ |
| No genes |
| a 2,3-dihydroxybenzoyl-glycyl-[DhbF non-ribosomal peptide synthase] + an L-threonyl-[DhbF non-ribosomal peptide synthase]→a 2,3-dihydroxybenzoyl-glycyl-L-arginyl-[DhbF non-ribosomal peptide synthase] + a [DhbF non-ribosomal peptide synthase] + H+ |
| No genes |
| 3 a 2,3-dihydroxybenzoyl-glycyl-L-arginyl-[DhbF non-ribosomal peptide synthase]→bacillibactin + 3 a [DhbF non-ribosomal peptide synthase] |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information