| cholesterol + dioxygen + a reduced [NADPH-hemoprotein reductase]→7α-hydroxycholesterol + an oxidized [NADPH-hemoprotein reductase] + H2O (EC 1.14.14.23) |
| No genes |
Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase:
7α-hydroxycholesterol + NAD+→7α-hydroxycholest-4-en-3-one + NADH + H+ (EC 1.1.1.181) |
| No genes |
| 7α-hydroxycholest-4-en-3-one + dioxygen + a reduced [NADPH-hemoprotein reductase]→7α,12α-dihydroxycholest-4-en-3-one + an oxidized [NADPH-hemoprotein reductase] + H2O (EC 1.14.14.139) |
| No genes |
Delta(4)-3-oxosteroid 5-beta-reductase:
7α-hydroxycholest-4-en-3-one + NADPH + H+→7α-hydroxy-5β-cholestan-3-one + NADP+ (EC 1.3.1.3) |
| No genes |
Delta(4)-3-oxosteroid 5-beta-reductase:
7α,12α-dihydroxycholest-4-en-3-one + NADPH + H+→7α,12α-dihydroxy-5β-cholestan-3-one + NADP+ (EC 1.3.1.3) |
| No genes |
3-alpha-hydroxysteroid dehydrogenase (A-specific) (in reverse):
7α-hydroxy-5β-cholestan-3-one + NAD(P)H + H+→5β-cholestane-3α,7α-diol + NAD(P)+ (EC 1.1.1.213) |
| No genes |
3-alpha-hydroxysteroid dehydrogenase (A-specific) (in reverse):
7α,12α-dihydroxy-5β-cholestan-3-one + NAD(P)H + H+→5β-cholestane-3α,7α,12α-triol + NAD(P)+ (EC 1.1.1.213) |
| No genes |
| 5β-cholestane-3α,7α-diol + dioxygen + 2 H+ + 2 a reduced adrenodoxin→(25R)-5β-cholestane-3α,7α,26-triol + 2 an oxidized adrenodoxin + H2O (EC 1.14.15.15) |
| No genes |
| 5β-cholestane-3α,7α,12α-triol + dioxygen + 2 H+ + 2 a reduced adrenodoxin→(25R)-5β-cholestane-3α,7α,12α,26-tetraol + 2 an oxidized adrenodoxin + H2O (EC 1.14.15.15) |
| No genes |
| (25R)-5β-cholestane-3α,7α,26-triol + dioxygen + 2 H+ + 2 a reduced adrenodoxin→(25R)-3α,7α-dihydroxy-5β-cholestan-26-al + 2 an oxidized adrenodoxin + 2 H2O (EC 1.14.15.15) |
| No genes |
| (25R)-5β-cholestane-3α,7α,12α,26-tetraol + dioxygen + 2 H+ + 2 a reduced adrenodoxin→(25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + 2 an oxidized adrenodoxin + 2 H2O (EC 1.14.15.15) |
| No genes |
| (25R)-3α,7α-dihydroxy-5β-cholestan-26-al + dioxygen + H+ + 2 a reduced adrenodoxin→(25R)-3α,7α-dihydroxy-5-β-cholestanate + 2 an oxidized adrenodoxin + H2O (EC 1.14.15.15) |
| No genes |
| (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + dioxygen + H+ + 2 a reduced adrenodoxin→(25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + 2 an oxidized adrenodoxin + H2O (EC 1.14.15.15) |
| No genes |
3-alpha,7-alpha-dihydroxy-5-beta-cholestanate--CoA ligase:
(25R)-3α,7α-dihydroxy-5-β-cholestanate + ATP + coenzyme A→(25R)-3α,7α-dihydroxy-5β-cholestanoyl-CoA + AMP + diphosphate (EC 6.2.1.28) |
| No genes |
Cholate--CoA ligase:
(25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + ATP + coenzyme A→(25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA + AMP + diphosphate (EC 6.2.1.7) |
| No genes |
Alpha-methylacyl-CoA racemase (in reverse):
(25R)-3α,7α-dihydroxy-5β-cholestanoyl-CoA→(25S)-3α,7α-dihydroxy-5β-cholestanoyl-CoA (EC 5.1.99.4) |
| mRNA_248 (8616) |
Alpha-methylacyl-CoA racemase (in reverse):
(25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA→(25S)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA (EC 5.1.99.4) |
| mRNA_248 (8616) |
| (25S)-3α,7α-dihydroxy-5β-cholestanoyl-CoA + an oxidized unknown electron carrier→(24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA + a reduced unknown two electron carrier |
| No genes |
| (25S)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA + an oxidized unknown electron carrier→(24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA + a reduced unknown two electron carrier |
| No genes |
hydratase:
(24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA + H2O→(24R,25R)-3α,7α,24-trihydroxy-5β-cholestanoyl CoA (EC 4.2.1.107) |
| No genes |
hydratase (in reverse):
(24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA + H2O→(24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA (EC 4.2.1.107) |
| No genes |
| (24R,25R)-3α,7α,24-trihydroxy-5β-cholestanoyl CoA + NAD+→3α,7α-dihydroxy-24-oxo-5β-cholestanoyl CoA + NADH + H+ |
| No genes |
| (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA + NAD+→3α,7α,12α-trihydroxy-24-oxo-5-β-cholestanoyl CoA + NADH + H+ |
| No genes |
Propanoyl-CoA C-acyltransferase (in reverse):
3α,7α-dihydroxy-24-oxo-5β-cholestanoyl CoA + coenzyme A→chenodeoxycholoyl-CoA + propanoyl-CoA (EC 2.3.1.176) |
| mRNA_5687 (14055) |
Propanoyl-CoA C-acyltransferase (in reverse):
3α,7α,12α-trihydroxy-24-oxo-5-β-cholestanoyl CoA + coenzyme A→choloyl-CoA + propanoyl-CoA (EC 2.3.1.176) |
| mRNA_5687 (14055) |
Bile acid-CoA:amino acid N-acyltransferase:
chenodeoxycholoyl-CoA + glycine→glycochenodeoxycholate + coenzyme A + H+ (EC 2.3.1.65) |
| No genes |
Bile acid-CoA:amino acid N-acyltransferase:
chenodeoxycholoyl-CoA + taurine→taurochenodeoxycholate + coenzyme A + H+ (EC 2.3.1.65) |
| No genes |
Bile acid-CoA:amino acid N-acyltransferase:
choloyl-CoA + glycine→glycocholate + coenzyme A + H+ (EC 2.3.1.65) |
| No genes |
Bile acid-CoA:amino acid N-acyltransferase:
choloyl-CoA + taurine→taurocholate + coenzyme A + H+ (EC 2.3.1.65) |
| No genes |