MetaCyc Pathway: L-carnitine biosynthesis in Rhodosporidium toruloides IFO0880

Add experiment(s):


Trimethyllysine dioxygenase:
N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + dioxygen→3-hydroxy-N6,N6,N6-trimethyl-L-lysine + CO2 + succinate (EC 1.14.11.8)
mRNA_812 (9180)
3-hydroxy-N6,N6,N6-trimethyl-L-lysine→4-trimethylammoniobutanal + glycine
mRNA_1299 (9667)
4-trimethylammoniobutyraldehyde dehydrogenase:
4-trimethylammoniobutanal + NAD+ + H2O→γ-butyrobetaine + NADH + 2 H+ (EC 1.2.1.47)
No genes
Gamma-butyrobetaine dioxygenase:
γ-butyrobetaine + 2-oxoglutarate + dioxygen→L-carnitine + CO2 + succinate (EC 1.14.11.1)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information