Monophenol monooxygenase:
2 L-tyrosine + dioxygen→2 L-dopa (EC 1.14.18.1) |
| No genes |
Dihydroxyphenylalanine transaminase:
L-dopa + 2-oxoglutarate→3-(3,4-dihydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.49) |
| No genes |
Tyrosine decarboxylase:
L-tyrosine + H+→tyramine + CO2 (EC 4.1.1.25; 4.1.1.28) |
| mRNA_1736 (10104) |
| mRNA_5309 (13677) |
Tyrosine 3-monooxygenase:
tyramine + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + dioxygen→dopamine + 4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin (EC 1.14.16.2) |
| No genes |
| 3-(3,4-dihydroxyphenyl)pyruvate + H+→3,4-dihydroxyphenylacetaldehyde + CO2 |
| No genes |
| 3,4-dihydroxyphenylacetaldehyde + dopamine→(S)-norlaudanosoline + H2O |
| No genes |
| (S)-norlaudanosoline + 3 S-adenosyl-L-methionine→(S)-reticuline + 3 S-adenosyl-L-homocysteine + 3 H+ |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information