MetaCyc Pathway: chorismate biosynthesis II (archaea) in Rhodosporidium toruloides IFO0880

Add experiment(s):


Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP
(EC 2.7.2.4)
mRNA_6294 (14662)
mRNA_8370 (16738)
D-glyceraldehyde 3-phosphate→enolaldehyde + phosphate
No genes
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate
(EC 1.2.1.11)
mRNA_1962 (10330)
enolaldehyde→methylglyoxal (spontaneous)
No genes
methylglyoxal + β-D-fructofuranose 1,6-bisphosphate→D-glyceraldehyde 3-phosphate + 6-deoxy-5-ketofructose 1-phosphate (EC 2.2.1.11)
No genes
6-deoxy-5-ketofructose 1-phosphate + L-aspartate 4-semialdehyde→2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + hydroxypyruvaldehyde phosphate (EC 2.2.1.10)
No genes
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + NAD+ + H2O→3-dehydroquinate + ammonium + NADH + H+ (EC 1.4.1.24)
No genes
3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O
(EC 4.2.1.10)
mRNA_2204 (10572)
mRNA_4451 (12819)
mRNA_5884 (14252)
mRNA_8034 (16402)
mRNA_669 (9037)
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+
(EC 1.1.1.25)
mRNA_5341 (13709)
mRNA_5884 (14252)
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+
(EC 2.7.1.71)
mRNA_5884 (14252)
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate
(EC 2.5.1.19)
mRNA_5884 (14252)
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate
(EC 4.2.3.5)
mRNA_5669 (14037)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information