MetaCyc Pathway: noradrenaline and adrenaline degradation in Rhodosporidium toruloides IFO0880

Add experiment(s):


Catechol O-methyltransferase:
(R)-noradrenaline + S-adenosyl-L-methionine→normetanephrine + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.6)
No genes
Monoamine oxidase:
(R)-noradrenaline + dioxygen + H2O→3,4-dihydroxyphenylglycolaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
No genes
Phenylethanolamine N-methyltransferase:
(R)-noradrenaline + S-adenosyl-L-methionine→(R)-adrenaline + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.28)
No genes
Monoamine oxidase:
(R)-adrenaline + dioxygen + H2O→3,4-dihydroxyphenylglycolaldehyde + hydrogen peroxide + methylamine (EC 1.4.3.4)
No genes
Catechol O-methyltransferase:
(R)-adrenaline + S-adenosyl-L-methionine→metanephrine + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.6)
No genes
Monoamine oxidase:
normetanephrine + dioxygen + H2O→3-methoxy-4-hydroxyphenylglycolaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
No genes
Alcohol dehydrogenase (in reverse):
3,4-dihydroxyphenylglycolaldehyde + NADH + H+→3,4-dihydroxyphenylglycol + NAD+ (EC 1.1.1.1)
mRNA_1661 (10029)
mRNA_1713 (10081)
mRNA_3282 (11650)
mRNA_3297 (11665)
mRNA_3939 (12307)
mRNA_4452 (12820)
mRNA_4507 (12875)
mRNA_5059 (13427)
mRNA_5186 (13554)
mRNA_5194 (13562)
mRNA_5579 (13947)
mRNA_5740 (14108)
mRNA_5741 (14109)
mRNA_7070 (15438)
mRNA_7110 (15478)
mRNA_8149 (16517)
mRNA_733 (9101)
Aldehyde dehydrogenase (NAD(+)):
3,4-dihydroxyphenylglycolaldehyde + NAD+ + H2O→3,4-dihydroxymandelate + NADH + 2 H+ (EC 1.2.1.3)
mRNA_2053 (10421)
mRNA_2289 (10657)
mRNA_2380 (10748)
mRNA_2756 (11124)
mRNA_3674 (12042)
mRNA_3891 (12259)
mRNA_4582 (12950)
mRNA_5058 (13426)
mRNA_7446 (15814)
mRNA_7955 (16323)
mRNA_8468 (16836)
mRNA_324 (8692)
Monoamine oxidase:
metanephrine + dioxygen + H2O→3-methoxy-4-hydroxyphenylglycolaldehyde + hydrogen peroxide + methylamine (EC 1.4.3.4)
No genes
Catechol O-methyltransferase:
3,4-dihydroxyphenylglycol + S-adenosyl-L-methionine→3-methoxy-4-hydroxyphenylglycol + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.6)
No genes
Catechol O-methyltransferase:
3,4-dihydroxymandelate + S-adenosyl-L-methionine→vanillylmandelate + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.6)
No genes
Alcohol dehydrogenase:
3-methoxy-4-hydroxyphenylglycol + NAD+→3-methoxy-4-hydroxyphenylglycolaldehyde + NADH + H+ (EC 1.1.1.1)
mRNA_1661 (10029)
mRNA_1713 (10081)
mRNA_3282 (11650)
mRNA_3297 (11665)
mRNA_3939 (12307)
mRNA_4452 (12820)
mRNA_4507 (12875)
mRNA_5059 (13427)
mRNA_5186 (13554)
mRNA_5194 (13562)
mRNA_5579 (13947)
mRNA_5740 (14108)
mRNA_5741 (14109)
mRNA_7070 (15438)
mRNA_7110 (15478)
mRNA_8149 (16517)
mRNA_733 (9101)
Aldehyde dehydrogenase (NAD(+)):
3-methoxy-4-hydroxyphenylglycolaldehyde + NAD+ + H2O→vanillylmandelate + NADH + 2 H+ (EC 1.2.1.3)
mRNA_2053 (10421)
mRNA_2289 (10657)
mRNA_2380 (10748)
mRNA_2756 (11124)
mRNA_3674 (12042)
mRNA_3891 (12259)
mRNA_4582 (12950)
mRNA_5058 (13426)
mRNA_7446 (15814)
mRNA_7955 (16323)
mRNA_8468 (16836)
mRNA_324 (8692)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information