MetaCyc Pathway: superpathway of seleno-compound metabolism in Rhodosporidium toruloides IFO0880

Add experiment(s):


Sulfate adenylyltransferase:
selenate + ATP + H+→adenosine 5'-phosphoselenate + diphosphate (EC 2.7.7.4)
mRNA_5075 (13443)
Serine O-acetyltransferase:
L-serine + acetyl-CoA→O-acetyl-L-serine + coenzyme A (EC 2.3.1.30)
No genes
Adenylyl-sulfate reductase (glutathione) (in reverse):
adenosine 5'-phosphoselenate + 2 glutathione→selenite + AMP + glutathione disulfide + 2 H+ (EC 1.8.4.9)
No genes
selenite + 4 glutathione + 2 H+→selenodiglutathione + glutathione disulfide + 3 H2O (spontaneous)
No genes
selenodiglutathione + NADPH + H+→glutathioselenol + glutathione + NADP+
No genes
glutathioselenol + NADPH + H+→hydrogen selenide + glutathione + NADP+
No genes
Cysteine synthase:
O-acetyl-L-serine + hydrogen selenide→L-selenocysteine + acetate + H+ (EC 2.5.1.47)
mRNA_3663 (12031)
mRNA_4738 (13106)
L-selenocysteine + S-adenosyl-L-methionine→Se-methyl-L-selenocysteine + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.280)
No genes
L-selenocysteine + O-phospho-L-homoserine→L-selenocystathionine + phosphate
No genes
Methionine gamma-lyase:
Se-methyl-L-selenocysteine + H2O→methaneselenol + ammonium + pyruvate (EC 4.4.1.11)
No genes
Cysteine-S-conjugate beta-lyase:
L-selenocystathionine + H2O→seleno-L-homocysteine + ammonium + pyruvate (EC 4.4.1.13)
No genes
2 methaneselenol + an oxidized unknown electron carrier→dimethyl diselenide + a reduced unknown two electron carrier (spontaneous)
No genes
5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase:
seleno-L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate→L-selenomethionine + tetrahydropteroyl tri-L-glutamate (EC 2.1.1.14)
mRNA_1457 (9825)
Methionine S-methyltransferase:
L-selenomethionine + S-adenosyl-L-methionine→Se-methyl-Se-L-methionine + S-adenosyl-L-homocysteine (EC 2.1.1.12)
No genes
Methionine gamma-lyase:
Se-methyl-Se-L-methionine + H2O→dimethyl selenide + 2-oxobutanoate + ammonium + H+ (EC 4.4.1.11)
No genes
Se-methyl-Se-L-methionine + H+→dimethylselenopropanoate-amine + CO2
No genes
dimethylselenopropanoate-amine + dioxygen + H2O→3-dimethylselenopropanal + ammonium + hydrogen peroxide
No genes
3-dimethylselenopropanal + an oxidized unknown electron carrier + H2O→dimethylselenoniopropanoate + a reduced unknown two electron carrier + H+
No genes
dimethylselenoniopropanoate→dimethyl selenide + acrylate + H+
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information