MetaCyc Pathway: diphthamide biosynthesis I (archaea) in Rhodosporidium toruloides IFO0880

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an L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine→a 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H+ (EC 2.5.1.108)
No genes
Diphthine synthase:
a 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2] + 3 S-adenosyl-L-methionine→a diphthine-[translation elongation factor 2] + 3 S-adenosyl-L-homocysteine + 3 H+ (EC 2.1.1.98)
mRNA_8137 (16505)
a diphthine-[translation elongation factor 2] + ammonium + ATP→a diphthamide-[translation elongation factor 2] + AMP + diphosphate + H+ (EC 6.3.1.14)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information