MetaCyc Pathway: GDP-L-fucose biosynthesis I (from GDP-D-mannose) in Rhodosporidium toruloides IFO0880

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GDP-mannose 4,6-dehydratase:
GDP-α-D-mannose→GDP-4-dehydro-α-D-rhamnose + H2O
(EC 4.2.1.47)
mRNA_2621 (10989)
mRNA_3255 (11623)
GDP-L-fucose synthase:
GDP-4-dehydro-α-D-rhamnose→GDP-4-dehydro-6-deoxy-β-L-galactose
(EC 1.1.1.271)
mRNA_1236 (9604)
GDP-L-fucose synthase (in reverse):
GDP-4-dehydro-6-deoxy-β-L-galactose + NADPH + H+→GDP-β-L-fucose + NADP+
(EC 1.1.1.271)
mRNA_1236 (9604)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information